Brief Information of the Compound and Protein
Compound Name
pladienolide E
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PubChem ID
CID: 52940868
Canonical SMILES
CC[C@H](O)[C@](C)(O)[C@H]1O[C@@H]1C[C@H](C)/C=C/C=C(\C)[C@H]1OC(=O)C[C@H](O)CC[C@@](C)(O)[C@@H](OC(C)=O)CC[C@@H]1C
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Compound Formula C30H50O9
Compound Structure
Protein Name
Splicing factor 3B subunit 3
Protein Classification
Other nuclear protein
Uniprot ID
Q15393
Gene Name
SF3B3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG Homo sapiens (Human)  1
1
IC50 = 58.9 nM
   TI
   LI
   LO
   TS
CL000202 WiDr Homo sapiens (Human)  1
1
IC50 = 65.2 nM
   TI
   LI
   LO
   TS