Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
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 PubChem ID
CID: 135398737
SID: 14826474
Canonical SMILES
CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
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Compound Formula C18H19ClN4
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Potassium channels
>
Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 323.59 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
IC50 = 191 nM
   TI
   LI
   LO
   TS
2
IC50 = 650 nM
   TI
   LI
   LO
   TS
3
Ki = 3080 nM
   TI
   LI
   LO
   TS
4
Ki = 4060 nM
   TI
   LI
   LO
   TS
5
Ki = 17000 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 190.55 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 320 nM
2 IC50 = 323.59 nM
3 IC50 = 901 nM
4 IC50 = 3200 nM
5 IC50 = 3981.07 nM