Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid
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 PubChem ID
CID: 74685737
SID: 14835656
Canonical SMILES
CC(C)(C(O)=O)c1ccc(cc1)C(O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1
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Compound Formula C32H39NO4
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Potassium channels
>
Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 23000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 21570 nM
   TI
   LI
   LO
   TS
2
IC50 = 23000 nM
   TI
   LI
   LO
   TS
3
IC50 = 65000 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 21379.62 nM
   TI
   LI
   LO
   TS
CL000309 NCTC clone 929
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
2
IC50 > 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22908.68 nM
2 Ki = 23000 nM