Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl)-3-(2-methylquinolin-4-yl)urea
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 PubChem ID
CID: 10173280
SID: 15167346
Canonical SMILES
Cc1cc(NC(=O)NCCN2CCC(O)(Cc3ccccc3)CC2)c2ccccc2n1
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Compound Formula C25H30N4O2
Compound Structure
Protein Name
 Protein Info 
Urotensin-2 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide receptor
Uniprot ID
Q9UKP6
Gene Name
UTS2R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 39 nM
   TI
   LI
   LO
   TS
CL000397 RMS13
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
2
Ki = 41 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 < 5 nM
   TI
   LI
   LO
   TS