Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-2-bromo-4,5-dimethoxy-N-(3-(1-methylpyrrolidin-3-yloxy)-4-(trifluoromethyl)phenyl)benzenesulfonamide
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 PubChem ID
CID: 21023902
SID: 163625521
Canonical SMILES
COc1cc(Br)c(cc1OC)S(=O)(=O)Nc1ccc(c(O[C@@H]2CCN(C)C2)c1)C(F)(F)F
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Compound Formula C20H22BrF3N2O5S
Compound Structure
Protein Name
 Protein Info 
Urotensin-2 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide receptor
Uniprot ID
Q9UKP6
Gene Name
UTS2R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000615 Chem-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CL000397 RMS13
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
2
Ki = 8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5.4 nM