Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine
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 PubChem ID
CID: 9948102
SID: 14922700
Canonical SMILES
Clc1ccc(CCCOCCCN2CCCCC2)cc1
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Compound Formula C17H26ClNO
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
Ki = 2.7 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
2
Ki = 2.4 nM
   TI
   LI
   LO
   TS
3
Ki = 2.512 nM
   TI
   LI
   LO
   TS
4
Ki = 30 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 2.512 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  9
1
Ki = 0.16 nM
   TI
   LI
   LO
   TS
2
Ki = 0.912 nM
   TI
   LI
   LO
   TS
3
Ki = 2.512 nM
   TI
   LI
   LO
   TS
4
Ki = 2.7 nM
   TI
   LI
   LO
   TS
5
Ki = 11.3 nM
   TI
   LI
   LO
   TS
6
Ki = 11.48 nM
   TI
   LI
   LO
   TS
7
Ki = 11.7 nM
   TI
   LI
   LO
   TS
8
Ki = 12 nM
   TI
   LI
   LO
   TS
9
Ki = 14.8 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 2.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.3 nM
2 Ki = 2.7 nM