Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid
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 PubChem ID
CID: 6603901
SID: 14854853
Canonical SMILES
CCCc1c(O)c(ccc1OCCCOc1ccc(OCC(O)=O)cc1)C(C)=O
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Compound Formula C22H26O7
Compound Structure
Protein Name
 Protein Info 
Peroxisome proliferator-activated receptor delta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group C
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Nuclear hormone receptor subfamily 1 group C member 2
Uniprot ID
Q03181
Gene Name
PPARD
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 6 nM
   TI
   LI
   LO
   TS
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
EC50 = 39 nM
   TI
   LI
   LO
   TS
2
EC50 = 125 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
2
EC50 = 21 nM
   TI
   LI
   LO
   TS
3
EC50 = 210 nM
   TI
   LI
   LO
   TS
4
EC50 = 640 nM
   TI
   LI
   LO
   TS
5
EC50 = 650 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 61 nM
2 Kd = 76.4 nM