Brief Information of the Compound and Protein
Compound Name
6-chloro-2a-[4-[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-1,3,4,5-tetrahydrobenzo[cd]indol-2-one
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PubChem ID
CID: 9911844
SID: 14882237
Canonical SMILES
Clc1ccc(cc1)C1=CCN(CCCCC23CCCc4c2c(NC3=O)ccc4Cl)CC1
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Compound Formula C26H28Cl2N2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 7
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
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Serotonin receptor
Uniprot ID
P34969
Gene Name
HTR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 7.244 nM
   TI
   LI
   LO
   TS
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
Ki = 7.244 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 7.24 nM
2 Ki = 7.244 nM