Brief Information of the Compound and Protein
Compound Name
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-pyridin-4-yl-ethyl)-isonicotinamide
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PubChem ID
CID: 44443253
Canonical SMILES
O=C(COc1ccc(cc1)C12CC3CC(CC(C3)C1)C2)Nc1cc(ccn1)C(=O)NCCc1ccncc1
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Compound Formula C31H34N4O3
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000275 AGS Homo sapiens (Human)  1
1
IC50 = 5200 nM
   TI
   LI
   LO
   TS
CL000273 Hep 3B2.1-7 Homo sapiens (Human)  1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CL000274 SK-HEP-1 Homo sapiens (Human)  1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS