Brief Information of the Compound and Protein
Compound Name
4-[(4'-fluorobenzyl)amino]-6,7-dimethoxyquinazoline hydrochloride
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PubChem ID
CID: 11552033
SID: 16654264
Canonical SMILES
COc1cc2ncnc(NCc3ccc(F)cc3)c2cc1OC.Cl
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Compound Formula C17H17ClFN3O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000052 A-431 Homo sapiens (Human)  1
1
IC50 = 47.7 nM
   TI
   LI
   LO
   TS
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 10.9 nM
   TI
   LI
   LO
   TS
CL000243 MCF-10A Homo sapiens (Human)  1
1
IC50 = 489 nM
   TI
   LI
   LO
   TS