Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride
    Show/Hide
 PubChem ID
CID: 53627818
SID: 15120660
Canonical SMILES
C[N+](C)(C)CCOC(N)=O.[Cl-]
    Show/Hide
Compound Formula C6H15ClN2O2
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P20309
Gene Name
CHRM3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9
 Cell Line Info 
Mus musculus (Mouse)  2
1
EC50 = 5011.87 nM
   TI
   LI
   LO
   TS
2
Ki = 6309.57 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 880 nM
   TI
   LI
   LO
   TS
2
Ki = 43651.58 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 51000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 22 nM
   TI
   LI
   LO
   TS
2
EC50 = 25 nM
   TI
   LI
   LO
   TS
3
EC50 = 15000 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
ED50 = 100 nM
   TI
   LI
   LO
   TS
CL000289 SK-N-SH
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 10600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 1800 nM
2 IC50 = 9100 nM
3 Ki = 20000 nM