Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
    Show/Hide
 PubChem ID
CID: 16078
SID: 14776764
Canonical SMILES
CCCCCc1cc(O)c2[C@@H]3C=C(C)CC[C@H]3C(C)(C)Oc2c1
    Show/Hide
Compound Formula C21H30O2
Compound Structure
Protein Name
 Protein Info 
Cannabinoid receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Cannabinoid receptor
Uniprot ID
P34972
Gene Name
CNR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 36 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 12.3 nM
   TI
   LI
   LO
   TS
2
Ki = 46 nM
   TI
   LI
   LO
   TS
3
Ki = 71.6 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
Ki = 32.2 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 9.5 nM
   TI
   LI
   LO
   TS
2
Ki = 42 nM
   TI
   LI
   LO
   TS
3
Ki = 71.6 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 25 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
EC50 = 1.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.193125 nM
2 Ki = 3.3 nM
3 Ki = 24 nM
4 Ki = 36 nM
5 Ki = 36.4 nM
6 Ki = 40 nM
7 Ki = 41 nM