Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BEPRIDIL HYDROCHLORIDE
    Show/Hide
 PubChem ID
CID: 2351
SID: 14755108
Canonical SMILES
CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1
    Show/Hide
Compound Formula C24H34N2O
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Potassium channels
>
Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 549.54 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
2
Ki = 184 nM
   TI
   LI
   LO
   TS
3
Ki = 291 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 549.54 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22.91 nM
2 IC50 = 430 nM
3 IC50 = 549.54 nM