Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
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 PubChem ID
CID: 3715
SID: 14754602
Canonical SMILES
COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1
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Compound Formula C19H16ClNO4
Compound Structure
Protein Name
 Protein Info 
Prostaglandin G/H synthase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P23219
Gene Name
PTGS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
2
IC50 = 39 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 12400 nM
   TI
   LI
   LO
   TS
CL000100 U-937
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
2
IC50 = 3 nM
   TI
   LI
   LO
   TS
3
IC50 = 20 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Activity = 2.934682 nM
2 IC50 = 10 nM
3 IC50 = 12 nM
4 IC50 = 20 nM
5 IC50 = 40 nM
6 IC50 = 50 nM
7 IC50 = 51 nM
8 IC50 = 100 nM
9 IC50 = 110 nM
10 IC50 = 150 nM
11 IC50 = 180 nM
12 IC50 = 200 nM
13 IC50 = 220 nM
14 IC50 = 250 nM
15 IC50 = 260 nM
16 IC50 = 463.1 nM
17 IC50 = 750 nM
18 IC50 = 1200 nM
19 IC50 = 1400 nM
20 IC50 = 1560 nM
21 IC50 = 3870 nM
22 IC50 = 3900 nM
23 IC50 = 5600 nM
24 IC50 = 12500 nM
25 Ka = 185185.1852 nM
26 Kd = 253 nM