Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one
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 PubChem ID
CID: 57363
SID: 12014292
Canonical SMILES
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C
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Compound Formula C23H36N2O2
Compound Structure
Protein Name
 Protein Info 
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P18405
Gene Name
SRD5A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 366 nM
   TI
   LI
   LO
   TS
CL000119 DU145
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 26.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 40 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 218 nM
   TI
   LI
   LO
   TS
2
IC50 = 453 nM
   TI
   LI
   LO
   TS
3
IC50 = 540 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 52 nM
2 IC50 = 150 nM
3 IC50 = 500 nM
4 Ki = 100 nM
5 Ki = 150 nM