Brief Information of the Compound and Protein
Compound Name
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
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PubChem ID
CID: 82146
SID: 87550948
Canonical SMILES
Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
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Compound Formula C24H28O2
Compound Structure
Protein Name
Retinoic acid receptor beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group B
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Nuclear hormone receptor subfamily 1 group B member 2
Uniprot ID
P10826
Gene Name
RARB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  2
1
EC50 = 282 nM
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 > 10000 nM
2 Kd > 1000 nM
3 Ki = 50 nM
4 Ki = 5353 nM
5 Ki > 550 nM
6 Ki > 800 nM
7 Ki > 1000 nM