Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic acid
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 PubChem ID
CID: 64929
SID: 15988368
Canonical SMILES
CC(C)(Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1)C(O)=O
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Compound Formula C17H15ClO4
Compound Structure
Protein Name
 Protein Info 
Peroxisome proliferator-activated receptor alpha
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group C
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Nuclear hormone receptor subfamily 1 group C member 1
Uniprot ID
Q07869
Gene Name
PPARA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 12000 nM
   TI
   LI
   LO
   TS
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 12000 nM
   TI
   LI
   LO
   TS
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
EC50 = 2646 nM
   TI
   LI
   LO
   TS
2
EC50 = 30000 nM
   TI
   LI
   LO
   TS
3
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 30000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 4500 nM
2 EC50 = 15000 nM
3 EC50 = 30000 nM
4 EC50 = 32050 nM
5 EC50 > 10000 nM
6 IC50 = 24000 nM
7 IC50 = 35000 nM
8 IC50 = 68000 nM
9 IC50 > 10000 nM
10 Ki = 35000 nM