Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione

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PubChem ID

CID: 6279

SID: 14853921

Canonical SMILES	C[C@H]1C[C@H]2[C@@H]3CC[C@](OC(C)=O)(C(C)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 Show/Hide
Compound Formula	C24H34O4

Compound Structure

Protein Name

Protein Info

Progesterone receptor

Protein Classification

Transcription factor

Nuclear receptor

Nuclear hormone receptor subfamily 3

Nuclear hormone receptor subfamily 3 group C

Nuclear hormone receptor subfamily 3 group C member 3

Uniprot ID

P06401

Gene Name

PGR

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000044	CV-1 Cell Line Info	Chlorocebus aethiops (Green monkey)	2
1	EC50 = 0.15 nM	TI LI LO TS
2	IC50 < 10000 nM	TI LI LO TS
CL000012	Sf21 Cell Line Info	Spodoptera frugiperda (Fall armyworm)	1
1	Ki = 0.34 nM	TI LI LO TS
CL000078	T-47D Cell Line Info	Homo sapiens (Human)	6
1	EC50 = 0.1 nM	TI LI LO TS
2	EC50 = 0.12 nM	TI LI LO TS
3	EC50 = 0.33 nM	TI LI LO TS
4	EC50 = 0.4 nM	TI LI LO TS
5	EC50 = 0.5 nM	TI LI LO TS
6	IC50 = 10.8 nM	TI LI LO TS

Biochemical Assays