Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium
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 PubChem ID
CID: 6603820
SID: 57304370
Canonical SMILES
Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O
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Compound Formula C17H17NO2
Compound Structure
Protein Name
 Protein Info 
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 35.7 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 7.2 nM
   TI
   LI
   LO
   TS
2
EC50 = 19 nM
   TI
   LI
   LO
   TS
3
Ki = 33 nM
   TI
   LI
   LO
   TS
CL000041 LTK-
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 14 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 6.2 nM
2 Ki = 1200 nM