General Information of the Protein
Protein ID
PT07686
Protein Name
Prostaglandin F2-alpha receptor
Secondarily
Protein Name
Prostanoid FP receptor
Gene Name
PTGFR
Sequence
MSINSSKQPASSAAGLIANTTCQTENRLSVFFSIIFMTVGIVSNSLAIAILMKAYQRFRRKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSVFGISMVFSGLCPLFLGSTMAIERCIGVTNPLFHSTKITSKHVKMILSGVCMFAVFVALLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSSLGLLALGISFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMVIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKENQQASSEAGL
    Show/Hide
Organism
Rattus norvegicus, Rat
Protein Classification
Unclassified protein
Function
Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum.
    Show/Hide
Uniprot ID
Primary ID:
P43118

Secondarily ID:
Q62787
    Show/Hide
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000011 , CHO
Compound ID Compound Name Compound Formula
CP0272414
US11149018, Example 34
   Show/Hide
C26H27BrClN3O3
 1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
Similar Protein(s) and Bioactivity Statistics
90% Identity
Protein ID Protein Name Protein Organism
PT04759 Prostaglandin F2-alpha receptor Mus musculus, Mouse
50% Identity
Protein ID Protein Name Protein Organism
PT01823 Prostaglandin F2-alpha receptor Homo sapiens, Human