General Information of the Protein
| Protein ID |
PT06057
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| Protein Name |
Beta-3 adrenergic receptor
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| Secondarily Protein Name |
Beta-3 adrenoreceptor
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| Gene Name |
ADRB3
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| Secondarily Gene Name |
B3AR
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| Sequence |
MAPWPHGNGSVASWPAAPTPTPDAANTSGLPGAPWAVALAGALLALEVLATVGGNLLVIVAIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGATLALTGRWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRRARAAVVLVWVVSAAVSFAPIMSKWWRVGADAEAQRCHSNPHCCAFASNIPYALLSSSVSFYLPLLVMLFVYARVFLVATRQLRLLRRELGRFPPAESPPAASRSRSPGPARRCASPAAVPSDRLRPARLLPLREHRALRTLGLIVGTFTLCWLPFFVANVMRALGGPSLVPSPALLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCRREEHRAAASPPGDPSAAPAALTSPAESSRCQALDGASWGIS
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| Organism |
Canis lupus familiaris, Dog, Canis familiaris
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| Protein Classification |
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Adrenergic receptor
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| Function |
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
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| Uniprot ID |
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| Ensembl ID | |||||
| Subcellular Location |
Cell membrane
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000011 , CHO
Similar Protein(s) and Bioactivity Statistics
50% Identity
| Protein ID | Protein Name | Protein Organism | |
| PT01493 | Beta-3 adrenergic receptor | Homo sapiens, Human | |
|---|---|---|---|
| PT04360 | Beta-3 adrenergic receptor | Rattus norvegicus, Rat | |
| PT06423 | Beta-3 adrenergic receptor | Macaca mulatta, Rhesus macaque | |