General Information of the Protein
| Protein ID |
PT00947
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| Protein Name |
Geranylgeranyl pyrophosphate synthase
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| Secondarily Protein Name |
(2E,6E)-farnesyl diphosphate synthase
Dimethylallyltranstransferase
Farnesyl diphosphate synthase
Farnesyltranstransferase
Geranylgeranyl diphosphate synthase
Geranyltranstransferase
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| Gene Name |
GGPS1
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| Sequence |
MEKTQETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTLGLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE
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| Organism |
Homo sapiens, Human
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| Protein Classification |
Enzyme
>
Transferase
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| Function |
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
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| Uniprot ID |
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| Ensembl ID | |||||
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| Subcellular Location |
Cytoplasm
Cytoplasm
Perinuclear region
Cytoplasm
Myofibril
Sarcomere
Z line
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000068 , A-549
Cell Line ID: CL000111 , MDA-MB-231
Cell Line ID: CL000207 , MIA PaCa-2