General Information of the Protein
Protein ID
PT00654
Protein Name
Lysophosphatidic acid receptor 5
Gene Name
LPAR5
Sequence
MPQTSFSPHLDAMFANSSANTSSTDSSVPQCRDYRSTHRLHMVVYSLVLATGLPLNALALWVFLRVLRVHSVVSVYMCNLAASDLLFTLSLPLRLSYYARHHWPFPDFLCQTSGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPLVARRLCLGVWALILLFAVPAARVHSPTTCKYENVTLSLCFESFSDELWKGRLLPLLLLAETLGFLLPLAAVVYSSGRVFWTLARPDATQSHRRQKTVRLLLANLIIFLLCFVPYNSTLAVYGLLRANLVKNSLQARDQVRGVLMIMVLLAGANCVLDPLVYYFSAEGFRNTLRNLGAPFHTRPLPTNGTRGELTEPPSESTQNTGQDATSQRLLQPANLGTRTDNGPQDSAL
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Organism
Rattus norvegicus, Rat
Protein Classification
Unclassified protein
Uniprot ID
D4ADR1
Ensembl ID
ENSG00000184574
Subcellular Location
Membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0408712
 Compound Info 
4-(azepane-1-carbonyl)-2-(1-ethyl-2,3-dihydroindol-6-yl)-6,7-dimethoxyisoquinolin-1-one
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C28H33N3O4
  1
1
IC50 = 110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0444436
 Compound Info 
2-(1-ethyl-2,3-dihydroindol-6-yl)-4-(4-fluoropiperidine-1-carbonyl)-6,7-dimethoxyisoquinolin-1-one
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C27H30FN3O4
  1
1
IC50 = 120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0963675
 Compound Info 
4-(Azepan-1-ylcarbonyl)-2-[3-(dimethylamino)phenyl]-6,7-dimethoxyisoquinolin-1(2H)-one hydrochloride
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C26H32ClN3O4
  1
1
IC50 = 130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556659
 Compound Info 
4-(azepane-1-carbonyl)-2-(4-ethylphenyl)-6,7-dimethoxyisoquinolin-1-one
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C26H30N2O4
  1
1
IC50 = 570 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0541326
 Compound Info 
4-(azepane-1-carbonyl)-2-(3,4-dimethylphenyl)-6,7-dimethoxyisoquinolin-1-one
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C26H30N2O4
  1
1
IC50 = 720 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0422902
 Compound Info 
2-(4-ethoxyphenyl)-4-(4-fluoropiperidine-1-carbonyl)-6,7-dimethoxyisoquinolin-1-one
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C25H27FN2O5
  1
1
IC50 = 750 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568901
 Compound Info 
4-(azepan-1-ylcarbonyl)-2-(4-ethoxyphenyl)-6,7-dimethoxy-isoquinolin-1-one
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C26H30N2O5
  1
1
IC50 = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0562553
 Compound Info 
2-(4-ethoxyphenyl)-N-hexyl-6,7-dimethoxy-N-methyl-1-oxoisoquinoline-4-carboxamide
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C27H34N2O5
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0408711
 Compound Info 
4-(azepane-1-carbonyl)-6,7-dimethoxy-2-propan-2-ylisoquinolin-1-one
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C21H28N2O4
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558199
 Compound Info 
4-[4-(azepane-1-carbonyl)-6,7-dimethoxy-1-oxoisoquinolin-2-yl]benzamide
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C25H27N3O5
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0545957
 Compound Info 
4-(azepane-1-carbonyl)-2-(4-fluorophenyl)-6,7-dimethoxyisoquinolin-1-one
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C24H25FN2O4
  1
1
IC50 > 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Similar Protein(s) and Bioactivity Statistics
50% Identity
Protein ID Protein Name Protein Organism
PT05651 Lysophosphatidic acid receptor 5 Homo sapiens, Human
 Protein Info