General Information of the Protein
Protein ID
PT05651
Protein Name
Lysophosphatidic acid receptor 5
Secondarily
Protein Name
G-protein coupled receptor 92
G-protein coupled receptor 93
Gene Name
LPAR5
Secondarily
Gene Name
GPR92
GPR93
Sequence
MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
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Organism
Homo sapiens, Human
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
EDG receptor
Function
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.
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Uniprot ID
Q9H1C0
Ensembl ID
ENSG00000184574
HGNC ID
HGNC:13307
Subcellular Location
Cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000555 , B103
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0482104
 Compound Info 
(2-hydroxy-3-phosphonooxypropyl) (Z)-octadec-9-enoate
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C21H41O7P
  1
1
EC50 = 140 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0125579
 Compound Info 
(R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-propyl ester
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C21H41O7P
  1
1
EC50 = 510 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0148963
 Compound Info 
2-[4-[4-[3-methyl-4-[[(1R)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic acid
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C27H24N2O5
  1
1
IC50 > 8000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Line ID: CL000466 , McA-RH7777
 Cell Line Info 
Biochemical Assays
Compound ID Compound Name Compound Formula
CP0128457
 Compound Info 
2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-5-carboxylic acid
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C21H12N2O7
  1
1 Ki = 292 nM
Clinical Information about the Protein
Target 1 ( Lysophosphatidic acid receptor 5 (LPAR5) )
Target Type Literature-reported Target
Similar Protein(s) and Bioactivity Statistics
50% Identity
Protein ID Protein Name Protein Organism
PT00654 Lysophosphatidic acid receptor 5 Rattus norvegicus, Rat
 Protein Info