General Information of the Protein
Protein ID
PT00605
Protein Name
FML2_HUMAN
Gene Name
FPRL2
Secondarily
Gene Name
hCG_91958
Sequence
METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
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Organism
Homo sapiens, Human
Protein Classification
Unclassified protein
Uniprot ID
Q6L5J4
Subcellular Location
Cell membrane
Membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000018 , HL-60
Compound ID Compound Name Compound Formula
CP0372534
(S)-6-amino-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-N-((5R,8S,11S,14S)-5-carbamoyl-15-(4-hydroxyphenyl)-8-isopropyl-11-(2-(methylthio)ethyl)-7,10,13-trioxo-2-thia-6,9,12-triazapentadecan-14-yl)hexanamide
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C41H61N9O7S2
 1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
CP0046087
(S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid
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C21H31N3O5S
 1
1
EC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0394900
N-(4-bromophenyl)-2-[3-methyl-6-oxo-5-(thiophen-2-ylmethyl)pyridazin-1-yl]acetamide
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C18H16BrN3O2S
 1
1
EC50 = 10200 nM
   TI
   LI
   LO
   TS
CP0387583
N-(4-iodophenyl)-2-[5-[(3-methoxyphenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]acetamide
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C21H20IN3O3
 1
1
EC50 = 13000 nM
   TI
   LI
   LO
   TS
CP0382870
N-(4-bromophenyl)-2-[5-[(3-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
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C20H18BrN3O3
 1
1
EC50 = 14600 nM
   TI
   LI
   LO
   TS
CP0396522
N-(4-bromophenyl)-2-[5-[(3-methoxyphenyl)methyl]-6-oxo-3-propan-2-ylpyridazin-1-yl]acetamide
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C23H24BrN3O3
 1
1
EC50 = 17400 nM
   TI
   LI
   LO
   TS
CP0382862
2-(5-benzyl-3-methyl-6-oxopyridazin-1-yl)-N-(4-fluorophenyl)acetamide
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C20H18FN3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0382863
N-(4-fluorophenyl)-2-[3-(4-fluorophenyl)-5-[(3-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
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C26H21F2N3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0382864
N-(1,3-benzodioxol-5-yl)-2-[3-(4-fluorophenyl)-5-[(3-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
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C27H22FN3O5
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0382865
N-(1,3-benzodioxol-5-yl)-2-[5-[(3-methoxyphenyl)methyl]-6-oxo-3-phenylpyridazin-1-yl]acetamide
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C27H23N3O5
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0382866
N-(4-bromophenyl)-2-[5-[(3-bromophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]acetamide
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C20H17Br2N3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0382867
2-[3-benzyl-5-[(4-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]-N-(4-bromophenyl)acetamide
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C27H24BrN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387809
N-(4-bromophenyl)-2-[5-[(3,5-dimethoxyphenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]acetamide
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C22H22BrN3O4
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387810
2-[3-(4-chlorophenyl)-5-[(3-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]-N-(4-fluorophenyl)acetamide
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C26H21ClFN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387812
2-[3-ethyl-5-[(3-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]-N-(4-iodophenyl)acetamide
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C22H22IN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387813
N-(4-bromophenyl)-2-[5-[(4-methoxyphenyl)methyl]-6-oxo-3-thiophen-2-ylpyridazin-1-yl]acetamide
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C24H20BrN3O3S
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387815
N-(4-bromophenyl)-2-[5-[(4-cyanophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]acetamide
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C21H17BrN4O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387817
N-(4-bromophenyl)-2-[5-[(4-methoxyphenyl)methyl]-3-(4-methylphenyl)-6-oxopyridazin-1-yl]acetamide
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C27H24BrN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387818
N-(1,3-benzodioxol-5-yl)-2-[5-[(3-methoxyphenyl)methyl]-6-oxo-3-thiophen-2-ylpyridazin-1-yl]acetamide
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C25H21N3O5S
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387819
2-[5-[(3,5-dimethoxyphenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]-N-(4-iodophenyl)acetamide
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C22H22IN3O4
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387820
N-(4-bromophenyl)-2-[5-(3-methoxybenzoyl)-3-methyl-6-oxopyridazin-1-yl]acetamide
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C21H18BrN3O4
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0387821
N-[2-[2-(4-bromoanilino)-2-oxoethyl]-6-methyl-3-oxopyridazin-4-yl]-3-methoxybenzamide
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C21H19BrN4O4
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0394901
N-(1,3-benzodioxol-5-yl)-2-(5-benzyl-3-methyl-6-oxopyridazin-1-yl)acetamide
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C21H19N3O4
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0394902
N-(4-bromophenyl)-2-[3-methyl-5-(naphthalen-1-ylmethyl)-6-oxopyridazin-1-yl]acetamide
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C24H20BrN3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0394903
N-(4-bromophenyl)-2-[3-methyl-6-oxo-5-(pyridin-3-ylmethyl)pyridazin-1-yl]acetamide
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C19H17BrN4O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396516
N-(1,3-benzodioxol-5-yl)-2-[3-(4-chlorophenyl)-5-[(3-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
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C27H22ClN3O5
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396517
N-(4-fluorophenyl)-2-[5-[(3-methoxyphenyl)methyl]-6-oxo-3-thiophen-2-ylpyridazin-1-yl]acetamide
   Show/Hide
C24H20FN3O3S
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396518
N-(4-bromophenyl)-2-[3-cyclohexyl-5-[(3-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C26H28BrN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396519
N-(4-bromophenyl)-2-[3-(4-chlorophenyl)-5-[(4-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
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C26H21BrClN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396520
N-(4-fluorophenyl)-2-[5-[(3-methoxyphenyl)methyl]-6-oxo-3-phenylpyridazin-1-yl]acetamide
   Show/Hide
C26H22FN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396524
N-(4-bromophenyl)-2-[3-methyl-6-oxo-5-(thiophen-3-ylmethyl)pyridazin-1-yl]acetamide
   Show/Hide
C18H16BrN3O2S
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396525
2-[4-acetyl-5-(4-methoxyanilino)-3-methyl-6-oxopyridazin-1-yl]-N-(4-bromophenyl)acetamide
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C22H21BrN4O4
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396526
N-(4-bromophenyl)-2-[5-[(3-methoxyphenyl)methyl]-6-oxo-3-phenylpyridazin-1-yl]acetamide
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C26H22BrN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396527
2-(5-benzyl-3-methyl-6-oxopyridazin-1-yl)-N-(4-bromophenyl)acetamide
   Show/Hide
C20H18BrN3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396528
2-[5-[(3-chlorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]-N-(4-iodophenyl)acetamide
   Show/Hide
C20H17ClIN3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396530
N-(4-bromophenyl)-2-[5-[(3-fluorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C20H17BrFN3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0396662
N-(4-bromophenyl)-2-[5-(furan-3-ylmethyl)-3-methyl-6-oxopyridazin-1-yl]acetamide
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C18H16BrN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0407624
4-bromo-N-[2-[2-(4-bromoanilino)-2-oxoethyl]-6-methyl-3-oxopyridazin-4-yl]benzamide
   Show/Hide
C20H16Br2N4O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0413860
N-(4-bromophenyl)-2-[3-methyl-6-oxo-5-[[4-(trifluoromethyl)phenyl]methyl]pyridazin-1-yl]acetamide
   Show/Hide
C21H17BrF3N3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0413862
N-(4-fluorophenyl)-2-[5-[(3-methoxyphenyl)methyl]-3-(4-methylphenyl)-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C27H24FN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0413863
N-(4-iodophenyl)-2-(3-methyl-6-oxo-4,5-dihydropyridazin-1-yl)acetamide
   Show/Hide
C13H14IN3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0413864
N-(1,3-benzodioxol-5-yl)-2-[3-(4-methoxyphenyl)-5-[(3-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C28H25N3O6
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0413865
N-(4-bromophenyl)-2-[3-(4-methoxyphenyl)-5-[(4-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C27H24BrN3O4
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0423047
N-(4-bromophenyl)-2-[5-(4-methoxyanilino)-3-methyl-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C20H19BrN4O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0423063
2-(5-amino-3-methyl-6-oxopyridazin-1-yl)-N-(4-bromophenyl)acetamide
   Show/Hide
C13H13BrN4O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0423064
4-[[2-[2-(4-bromoanilino)-2-oxoethyl]-6-methyl-3-oxopyridazin-4-yl]methyl]benzamide
   Show/Hide
C21H19BrN4O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0432405
N-(4-iodophenyl)-2-(3-methyl-6-oxopyridazin-1-yl)acetamide
   Show/Hide
C13H12IN3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0433041
N-(4-bromophenyl)-2-[3-(4-fluorophenyl)-5-[(4-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C26H21BrFN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0435699
N-(1,3-benzodioxol-5-yl)-2-[5-[(3-methoxyphenyl)methyl]-3-(4-methylphenyl)-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C28H25N3O5
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0482517
N-(4-bromophenyl)-2-[5-(4-methoxyphenyl)-3-methyl-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C20H18BrN3O3
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0482518
N-(4-bromophenyl)-2-[5-[(3-chlorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C20H17BrClN3O2
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0482519
N-(4-fluorophenyl)-2-[3-(4-methoxyphenyl)-5-[(3-methoxyphenyl)methyl]-6-oxopyridazin-1-yl]acetamide
   Show/Hide
C27H24FN3O4
 1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS
Similar Protein(s) and Bioactivity Statistics
50% Identity
Protein ID Protein Name Protein Organism
PT02590 N-formyl peptide receptor 2 Homo sapiens, Human