General Information of the Protein
| Protein ID |
PT00057
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| Protein Name |
Dihydrofolate reductase
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| Gene Name |
DFRA
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| Secondarily Gene Name |
GBAA_2237
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| Sequence |
MIVSFMVAMDENRVIGKDNNLPWRLPSELQYVKKTTMGHPLIMGRKNYEAIGRPLPGRRNIIVTRNEGYHVEGCEVAHSVEEVFELCKNEEEIFIFGGAQIYDLFLPYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGLTDEKNPYTYYYHVYEKQQ
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| Organism |
Bacillus anthracis
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| Protein Classification |
Enzyme
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Oxidoreductase
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| Function |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
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| Uniprot ID |
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000338 , DV3-M15
Biochemical Assays