Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-methyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-yl]pyrimidine-2,4-diamine
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 PubChem ID
CID: 16110337
SID: 24757165
Canonical SMILES
COc1cc(CC#Cc2c(C)nc(N)nc2N)cc(OC)c1OC
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Compound Formula C17H20N4O3
Compound Structure
Protein Name
 Protein Info 
Dihydrofolate reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
Q81R22
Gene Name
DFRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000338 DV3-M15
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 3700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3700 nM
2 Ki = 1250 nM