Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
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 PubChem ID
CID: 5578
SID: 14824824
Canonical SMILES
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
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Compound Formula C14H18N4O3
Compound Structure
Protein Name
 Protein Info 
Dihydrofolate reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
Q81R22
Gene Name
DFRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000338 DV3-M15
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 71000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 71400 nM
2 IC50 = 77000 nM
3 Ki = 24100 nM