| Compound ID |
Compound Name |
Compound Formula |
|
CP0373978
|
4'-(2-(5-(cycloheptylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
EC50 = 5.7 nM
|
|
|
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CP0401461
|
4'-(2-(5-(3,3-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
EC50 = 6.2 nM
|
|
|
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CP0401431
|
4'-(2-(5-neopentyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C23H26N2O2
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
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CP0447838
|
4'-(2-(5-(cyclobutylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C23H24N2O2
|
1
|
| 1 |
EC50 = 7.1 nM
|
|
|
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CP0384386
|
4'-(2-(5-(cyclohexylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C25H28N2O2
|
1
|
| 1 |
EC50 = 7.3 nM
|
|
|
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CP0401439
|
4'-(2-(5-(3-fluorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C25H21FN2O2
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
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CP0402259
|
4'-(2-(5-(cyclopentylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C24H26N2O2
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
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CP0373921
|
4'-(2-(5-(2,3-difluorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C25H20F2N2O2
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0440147
|
4'-(2-(5-(2-methylbenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C26H24N2O2
|
1
|
| 1 |
EC50 = 9.3 nM
|
|
|
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CP0440150
|
4'-(2-(5-(2-fluorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C25H21FN2O2
|
1
|
| 1 |
EC50 = 9.5 nM
|
|
|
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CP0365995
|
4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C24H28N2O2
|
1
|
| 1 |
EC50 = 9.6 nM
|
|
|
|
CP0401437
|
4'-(2-(5-isopentyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C23H26N2O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0373976
|
4'-(2-(5-benzyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H22N2O2
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0401424
|
4'-(2-(5-cyclohexyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C24H26N2O2
|
1
|
| 1 |
EC50 = 14.7 nM
|
|
|
|
CP0401436
|
4'-(2-(5-(3-cyanobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C26H21N3O2
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
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CP0210909
|
(2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]-3-(4-{[1-(trifluoromethyl)cyclopropyl]methyl}-1H-imidazol-2-yl)propan-2-ol
Show/Hide
|
C20H18F6N4O
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
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CP0373715
|
4'-(2-(5-(2-chlorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C25H21ClN2O2
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0410792
|
1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutane-1-carboxamide
Show/Hide
|
C25H20F6N4O4S
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0436009
|
N-methyl-1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutane-1-carboxamide
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|
C26H22F6N4O4S
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0373918
|
4'-(2-(5-((tetrahydro-2H-pyran-4-yl)methyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C24H26N2O3
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0504219
|
2-methyl-2-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]propanamide
Show/Hide
|
C24H20F6N4O4S
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
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CP0440144
|
4'-(2-(5-(2-ethyl-2-methylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H30N2O2
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0440149
|
4'-(2-(5-(3-chlorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H21ClN2O2
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
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CP0447839
|
4'-(2-(5-(2-cyclohexylethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0401426
|
4'-(2-(5-(4-fluorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H21FN2O2
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0191374
|
3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazole
Show/Hide
|
C25H22F3N5O3S
|
1
|
| 1 |
EC50 = 57 nM
|
|
|
|
CP0315939
|
6-(4-tert-butylphenyl)sulfonyl-7-pyridin-3-yl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C28H25F3N4O2S
|
1
|
| 1 |
EC50 = 58 nM
|
|
|
|
CP0385699
|
2-[3-[2-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]propan-2-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C28H25F6N5O5S
|
1
|
| 1 |
EC50 = 67 nM
|
|
|
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CP0401440
|
4'-(2-(5-(cyclopropylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C22H22N2O2
|
1
|
| 1 |
EC50 = 72 nM
|
|
|
|
CP0402258
|
4'-(2-(5-(3-methylbenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
EC50 = 75 nM
|
|
|
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CP0385700
|
2-[3-[1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutyl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C29H25F6N5O5S
|
1
|
| 1 |
EC50 = 76 nM
|
|
|
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CP0192143
|
3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-4H-1,2,4-oxadiazol-5-one
Show/Hide
|
C25H22F3N5O4S
|
1
|
| 1 |
EC50 = 76 nM
|
|
|
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CP0401435
|
4'-(2-(5-(3-methoxybenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
EC50 = 79 nM
|
|
|
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CP0179883
|
2-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C28H28F3N5O4S
|
1
|
| 1 |
EC50 = 83 nM
|
|
|
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CP0110516
|
(1S)-1-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]ethanol
Show/Hide
|
C27H26F3N5O4S
|
1
|
| 1 |
EC50 = 89 nM
|
|
|
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CP0513491
|
4'-(2-(5-butyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
EC50 = 93 nM
|
|
|
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CP0315938
|
[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]methanol
Show/Hide
|
C26H24F3N5O4S
|
1
|
| 1 |
EC50 = 93 nM
|
|
|
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CP0194393
|
2-[3-[2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]sulfonyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C25H19F6N5O4S
|
1
|
| 1 |
EC50 = 95 nM
|
|
|
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CP0260398
|
2-[3-[6-[4-(difluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C25H20F5N5O5S
|
1
|
| 1 |
EC50 = 99 nM
|
|
|
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CP0401438
|
4'-(2-(5-(4-chlorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H21ClN2O2
|
1
|
| 1 |
EC50 = 102 nM
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CP0315941
|
6-(4-tert-butylphenyl)sulfonyl-7-(1-methylpyrazol-4-yl)-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C27H26F3N5O2S
|
1
|
| 1 |
EC50 = 102 nM
|
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CP0315773
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6-(4-tert-butylphenyl)sulfonyl-7-piperidin-4-yl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C28H31F3N4O2S
|
1
|
| 1 |
EC50 = 115 nM
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CP0256765
|
2-[3-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C25H19F6N5O5S
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
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CP0315940
|
(1R)-1-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]ethanol
Show/Hide
|
C27H26F3N5O4S
|
1
|
| 1 |
EC50 = 134 nM
|
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CP0085078
|
2-[3-[6-(4-propan-2-ylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C27H26F3N5O4S
|
1
|
| 1 |
EC50 = 147 nM
|
|
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CP0373923
|
4'-(2-(5-(4-methylbenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
EC50 = 162 nM
|
|
|
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CP0384384
|
4'-(2-(5-(2-methoxybenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
EC50 = 163 nM
|
|
|
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CP0407688
|
4'-(2-(5-butyl-1H-imidazol-2-yl)pentyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H30N2O2
|
1
|
| 1 |
EC50 = 165 nM
|
|
|
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CP0401434
|
4'-(2-(5-phenethyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
EC50 = 174 nM
|
|
|
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CP0402261
|
4'-(2-(5-butyl-1H-imidazol-2-yl)propyl)biphenyl-2-carboxylic acid
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
EC50 = 184 nM
|
|
|
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CP0373910
|
4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H30N2O3
|
1
|
| 1 |
EC50 = 237.5 nM
|
|
|
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CP0402260
|
4'-(2-(5-butyl-1H-imidazol-2-yl)butyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
EC50 = 340 nM
|
|
|
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CP0401433
|
4'-(3-(5-butyl-1H-imidazol-2-yl)propyl)biphenyl-2-carboxylic acid
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
EC50 = 382 nM
|
|
|
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CP0407687
|
4'-(2-(5-(4-methoxybenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
EC50 = 513 nM
|
|
|
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CP0440145
|
4'-(2-(5-butyl-1H-imidazol-2-yl)hexyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H32N2O2
|
1
|
| 1 |
EC50 = 527 nM
|
|
|
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CP0373979
|
4'-(2-(5-(2-cyanobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H21N3O2
|
1
|
| 1 |
EC50 = 642 nM
|
|
|
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CP0470281
|
4'-(2-(5-(4-cyanobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H21N3O2
|
1
|
| 1 |
EC50 = 723 nM
|
|
|
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CP0373913
|
4'-(2-(5-phenyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H20N2O2
|
1
|
| 1 |
EC50 = 872 nM
|
|
|
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CP0440148
|
4'-(2-(5-butyl-1H-imidazol-2-yl)-3-methylbutyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H30N2O2
|
1
|
| 1 |
EC50 = 2240 nM
|
|
|
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CP0401462
|
4'-(2-(5-tert-butyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
EC50 = 2745 nM
|
|
|
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CP0384385
|
4'-((5-butyl-1H-imidazol-2-yl)methyl)biphenyl-2-carboxylic acid
Show/Hide
|
C21H22N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0850185
|
4'-(2-(5-butyl-1H-imidazol-2-yl)vinyl)biphenyl-2-carboxylic acid
Show/Hide
|
C22H22N2O2
|
1
|
| 1 |
EC50 = 10000 nM
|
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