Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]-3-(4-{[1-(trifluoromethyl)cyclopropyl]methyl}-1H-imidazol-2-yl)propan-2-ol
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 PubChem ID
CID: 49871766
SID: 104546702
Canonical SMILES
O[C@@](Cc1ncc(CC2(CC2)C(F)(F)F)[nH]1)(c1ccc(cc1)-n1cccn1)C(F)(F)F
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Compound Formula C20H18F6N4O
Compound Structure
Protein Name
 Protein Info 
Bombesin receptor subtype-3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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GRP-related receptor
Uniprot ID
O54798
Gene Name
BRS3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
CL000866 HEK293 AequoScreen
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.4 nM
2 Ki = 1.6 nM