| Compound ID |
Compound Name |
Compound Formula |
|
CP0390993
|
(2R,3'S)-1',1',3'-trimethyl-6-pentylspiro[3H-1-benzofuran-2,2'-cyclohexane]-4-ol
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|
C21H32O2
|
2
|
| 1 |
EC50 = 3300 nM
|
|
|
| 2 |
IC50 = 4300 nM
|
|
|
|
CP0390991
|
2-methyl-2-[4-methyl-4-(4-methylphenyl)pentyl]-7-pentyl-3,4-dihydrochromen-5-ol
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|
C28H40O2
|
2
|
| 1 |
EC50 = 18000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0426148
|
N-[4-cyclobutyl-5-(2-piperidin-1-ylethyl)-1,3-thiazol-2-yl]-1-(5-fluoropyridin-2-yl)-5-methylpyrazole-4-carboxamide;dihydrochloride
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|
C24H31Cl2FN6OS
|
1
|
| 1 |
IC50 = 0.32 nM
|
|
|
|
CP0402968
|
N-[4-cyclobutyl-5-(2-piperidin-1-ylethyl)-1,3-thiazol-2-yl]-1-(5-fluoropyridin-2-yl)-3-methylpyrazole-4-carboxamide;dihydrochloride
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|
C24H31Cl2FN6OS
|
1
|
| 1 |
IC50 = 0.73 nM
|
|
|
|
CP0488039
|
N-[4-cyclobutyl-5-(2-piperidin-1-ylethyl)-1,3-thiazol-2-yl]-1-(4-fluorophenyl)-5-methylpyrazole-4-carboxamide;dihydrochloride
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|
C25H32Cl2FN5OS
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0499671
|
7-ethoxy-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
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|
C39H43F3N4O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0113739
|
7-bromo-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
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|
C37H38BrF3N4O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0076959
|
N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
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|
C36H39F3N4O
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0436514
|
6-bromo-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
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|
C36H35BrF6N4O
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0441174
|
7-methoxy-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
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|
C38H41F3N4O2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0535887
|
N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
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|
C37H39F3N4O
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0547180
|
3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
Show/Hide
|
C36H36F6N4O
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0465745
|
7-bromo-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
Show/Hide
|
C36H35BrF6N4O
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0499701
|
7-ethoxy-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
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|
C38H40F6N4O2
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0391694
|
3-[(4-morpholin-4-ylpiperidin-1-yl)methyl]-N-[(1S)-1-phenylethyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
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|
C35H37F3N4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0436512
|
7-methoxy-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1R)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
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|
C37H38F6N4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0410163
|
N-[(1S)-1-phenylpropyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
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|
C37H41F3N4O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0436513
|
2-(3-chlorophenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
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|
C35H39ClN4O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0465746
|
3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]-N-[(1S)-2,2,2-trifluoro-1-phenylethyl]quinoline-4-carboxamide
Show/Hide
|
C36H36F6N4O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0441176
|
2-(3-methylphenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
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|
C36H42N4O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0391698
|
2-(4-chlorophenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
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|
C35H39ClN4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0454760
|
N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[4-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C36H39F3N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0391692
|
N-[(1S)-2-methyl-1-phenylpropyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C38H43F3N4O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0391696
|
N-(2-phenylpropan-2-yl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C37H41F3N4O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0465743
|
N-benzyl-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C35H37F3N4O
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0509505
|
2-(4-methylphenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C36H42N4O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0101210
|
2-nitro-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzamide
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|
C21H23F3N4O5S
|
3
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 660 nM
|
|
|
| 3 |
IC50 = 2100 nM
|
|
|
|
CP0350860
|
2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
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|
C26H28F3N3O2
|
1
|
| 1 |
IC50 = 133 nM
|
|
|
|
CP0473294
|
3,5-dimethoxy-N-[5-(4-methylpiperazin-1-yl)-4-phenyl-1,3-thiazol-2-yl]benzamide;dihydrochloride
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|
C23H28Cl2N4O3S
|
1
|
| 1 |
IC50 = 137 nM
|
|
|
|
CP0076960
|
2-phenyl-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C35H40N4O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0391697
|
2-(4-methoxyphenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C36H42N4O2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0410130
|
3-[[4-(dimethylamino)piperidin-1-yl]methyl]-N-[(1S)-1-phenylethyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C33H35F3N4O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0513148
|
2-fluoro-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzamide
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|
C21H23F4N3O3S
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0446877
|
4-(pentafluoro-lambda6-sulfanyl)-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide
Show/Hide
|
C20H24F5N3O3S2
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0391695
|
N-[(1R)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C36H39F3N4O
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0534800
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-2,4-bis(trifluoromethyl)benzamide
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|
C22H23F6N3O3S
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0399852
|
2-(3-methoxyphenyl)-N-[(1S)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C36H42N4O2
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0410162
|
2-phenyl-N-[(1R)-1-phenylethyl]-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]quinoline-4-carboxamide
Show/Hide
|
C35H40N4O
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0391693
|
N-[(1S)-1-phenylethyl]-3-[(4-piperazin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C35H38F3N5O
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0409612
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C21H24F3N3O3S
|
1
|
| 1 |
IC50 = 940 nM
|
|
|
|
CP0458444
|
4-tert-butyl-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide
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|
C24H33N3O3S
|
1
|
| 1 |
IC50 = 1050 nM
|
|
|
|
CP0457708
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H24F3N3O3S
|
1
|
| 1 |
IC50 = 1940 nM
|
|
|
|
CP0461936
|
2-amino-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C21H25F3N4O3S
|
1
|
| 1 |
IC50 = 2920 nM
|
|
|
|
CP0315551
|
2,4-dichloro-N-propan-2-yl-N-[2-(propan-2-ylamino)ethyl]benzenesulfonamide
Show/Hide
|
C14H22Cl2N2O2S
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0404307
|
4-(3-chloropyridin-2-yl)-N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide
Show/Hide
|
C25H27ClN4O3S
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0396602
|
(8aR,10aS)-8,8,10a-trimethyl-3-pentyl-6,7,8a,9-tetrahydro-5H-xanthen-1-ol
Show/Hide
|
C21H32O2
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0523314
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]benzamide
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|
C20H25N3O3S
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0404306
|
N-[4-(dimethylsulfamoyl)phenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C16H15F3N2O3S
|
1
|
| 1 |
IC50 = 5740 nM
|
|
|
|
CP0450624
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-pyridin-2-ylbenzamide
Show/Hide
|
C25H28N4O3S
|
1
|
| 1 |
IC50 = 6490 nM
|
|
|
|
CP0404308
|
N-[4-(4-propan-2-ylpiperazine-1-carbonyl)phenyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C22H24F3N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0471665
|
N-[4-(4-propan-2-ylpiperazin-1-yl)sulfonylphenyl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C20H24F3N3O4S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0465744
|
N-[(1S)-1-phenylethyl]-3-(piperidin-1-ylmethyl)-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C31H30F3N3O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0465747
|
3-[(4-cyclohexylpiperidin-1-yl)methyl]-N-[(1S)-1-phenylethyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
Show/Hide
|
C37H40F3N3O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0390986
|
(2R,3'R)-1',1',3'-trimethyl-6-pentylspiro[3H-1-benzofuran-2,2'-cyclohexane]-4-ol
Show/Hide
|
C21H32O2
|
1
|
| 1 |
IC50 = 39700 nM
|
|
|
|
CP0420446
|
bis[(1S)-1-(4-chlorophenyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methanone
Show/Hide
|
C35H34Cl2N2O5
|
1
|
| 1 |
IC50 = 81500 nM
|
|
|
|
CP0420471
|
bis[(1S)-6,7-dimethoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl]methanone
Show/Hide
|
C35H36N2O5
|
1
|
| 1 |
IC50 = 82600 nM
|
|
|
|
CP0420447
|
bis[(1S)-1-(4-fluorophenyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methanone
Show/Hide
|
C35H34F2N2O5
|
1
|
| 1 |
IC50 = 96200 nM
|
|
|
|
CP0390989
|
(7R,8aR,10aR)-7-iodo-8,8,10a-trimethyl-3-pentyl-6,7,8a,9-tetrahydro-5H-xanthen-1-ol
Show/Hide
|
C21H31IO2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0396601
|
(8aR,10aR)-8,8,10a-trimethyl-3-pentyl-6,7,8a,9-tetrahydro-5H-xanthen-1-ol
Show/Hide
|
C21H32O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0423849
|
(3Z,6R,11aS)-7,8,10-trimethoxy-9-methyl-6-phenyl-3-[(2,4,5-trimethoxy-3-methylphenyl)methylidene]-11,11a-dihydro-6H-pyrazino[1,2-b]isoquinoline-1,4-dione
Show/Hide
|
C33H36N2O8
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0375248
|
4-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-[[4-(trifluoromethoxy)phenyl]methyl]sulfamoyl]benzoic acid
Show/Hide
|
C21H13ClF6N2O5S
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
