1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)-3-(4-hydroxyphenyl)propan-1-one

4-Chloro-3-(4-cyclopropylbenzyl)-1-(beta-D-xylopyranosyl)-1Hindole

3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)propan-1-one

4-Chloro-3-(4-methoxybenzyl)-1-(beta-D-xylopyranosyl)-1H-indole

4-Chloro-3-(4-hydroxybenzyl)-1-(beta-D-xylopyranosyl)-1H-indole

4-Chloro-3-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-1-(beta-Dxylopyranosyl)-1H-indole

4-Bromo-3-(4-cyclopropylbenzyl)-1-(beta-D-xylopyranosyl)-1Hindole

(2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol

4-Chloro-3-[4-(methylsulfanyl)benzyl]-1-(beta-D-xylopyranosyl)-1H-indole

4-Chloro-3-[4-(N,N-dimethylamino)benzyl]-1-(beta-D-xylopyranosyl)-1H-indole

(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-[(E)-hydroxyiminomethyl]oxane-3,4,5-triol

4-chloro-N-[(E)-[(2R,3S,4R,5R,6S)-6-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3,4,5-trihydroxyoxan-2-yl]methylideneamino]benzamide

(2R,3S,4R,5R,6S)-2-[(E)-(benzylhydrazinylidene)methyl]-6-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]oxane-3,4,5-triol

(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-[(methoxyamino)methyl]oxane-3,4,5-triol

(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-[(E)-methoxyiminomethyl]oxane-3,4,5-triol

(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-[(hydroxyamino)methyl]oxane-3,4,5-triol

(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-[(E)-(2-hydroxyethylhydrazinylidene)methyl]oxane-3,4,5-triol

N-[(E)-[(2R,3S,4R,5R,6S)-6-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-3,4,5-trihydroxyoxan-2-yl]methylideneamino]benzamide

C-aryl glucoside, 5

(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methoxyphenyl)methyl]phenoxy}oxane-3,4,5-triol

US9034921, E001

US9034921, E016

(2S,3R,4R,6R)-2-[4-chloro-2-hydroxy-5-[(4-methoxyphenyl)methyl]phenyl]-5,5-difluoro-6-(hydroxymethyl)oxane-3,4-diol

US9034921, E021

LP-802034

(2S,3R,4R,5S,6R)-2-[5-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-2-hydroxy-4-methoxyphenyl]-5-fluoro-6-(hydroxymethyl)-5-methyloxane-3,4-diol

US9034921, E005

(2S,3R,4R,6R)-2-[4-chloro-5-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-2-hydroxyphenyl]-5,5-difluoro-6-(hydroxymethyl)oxane-3,4-diol

(2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-methoxybenzyl)phenyl)-6-methyltetrahydro-2H-pyran-3,4,5-triol

US9034921, E156

(2S,3R,4R,6R)-2-[5-(1-benzothiophen-2-ylmethyl)-4-chloro-2-hydroxyphenyl]-5,5-difluoro-6-(hydroxymethyl)oxane-3,4-diol

(2S,3R,4R,6R)-2-[5-(3,4-dihydro-2H-chromen-6-ylmethyl)-2-hydroxy-4-methoxyphenyl]-5,5-difluoro-6-(hydroxymethyl)oxane-3,4-diol

(2S,3R,4R,6R)-2-[4-chloro-2-hydroxy-5-[(3-methoxyphenyl)methyl]phenyl]-5,5-difluoro-6-(hydroxymethyl)oxane-3,4-diol

(3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)-6-methylspiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

(1S,3'R,4'S,5'S,6'R)-5-chloro-6-(4-ethylbenzyl)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triol

US9034921, E171

(2S,3R,4R,6R)-2-[5-(1-benzothiophen-2-ylmethyl)-2-hydroxy-4-methoxyphenyl]-5,5-difluoro-6-(hydroxymethyl)oxane-3,4-diol

(5S,6R,7R,8S)-5-(3-(4-ethylbenzyl)-4-methylphenyl)-4-oxaspiro[2.5]octane-6,7,8-triol

(2S,3R,4R,6R)-2-[5-(1-benzothiophen-2-ylmethyl)-4-chloro-2-methoxyphenyl]-5,5-difluoro-6-(hydroxymethyl)oxane-3,4-diol

(1R,2S,3R,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-(difluoromethoxy)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-methoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

CANAGLIFLOZIN

(2S,3R,4R,5S,6R)-2-[4-chloro-5-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-2-hydroxyphenyl]-5-fluoro-6-(hydroxymethyl)-5-methyloxane-3,4-diol

(2S,3R,4R,5S,6R)-2-[5-(1-benzothiophen-2-ylmethyl)-4-chloro-2-hydroxyphenyl]-5-fluoro-6-(hydroxymethyl)-5-methyloxane-3,4-diol

US9034921, E172

(5S,6R,7R,8S)-5-(3-(4-methoxybenzyl)-4-methylphenyl)-4-oxaspiro[2.5]octane-6,7,8-triol

(3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6-ethynyl-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

(1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-1-(hydroxymethyl)-6,8-dioxa-bicyclo[3.2.1]octane-2,3,4-triol

US9034921, E019

(1R,2S,3R,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-methylsulfanyl-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

(1S,2S,3S,4R,5S)-1-(Hydroxymethyl)-5-[3-(4-methoxybenzyl)-4-methylphenyl]-6,8-dioxa-bicyclo[3.2.1]octane-2,3,4-triol

(1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-methoxybenzyl)phenyl]-1-(hydroxymethyl)-6,8-dioxa-bicyclo[3.2.1]octane-2,3,4-triol

US9034921, E020

(2S,3R,4R,6R)-2-[5-(2,3-dihydro-1-benzofuran-5-ylmethyl)-2-hydroxy-4-methoxyphenyl]-5,5-difluoro-6-(hydroxymethyl)oxane-3,4-diol

(2S,3R,4R,6R)-2-[5-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-2-hydroxy-4-methoxyphenyl]-5,5-difluoro-6-(hydroxymethyl)oxane-3,4-diol

1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene

(1S,2S,3S,4R,5S)-5-[3-(4-Ethoxybenzyl)-4-methylphenyl]-1-(hydroxymethyl)-6,8-dioxa-bicyclo[3.2.1]octane-2,3,4-triol

(1R,2S,3R,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-pyridin-2-ylsulfanyl-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

(1S,2S,3R,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-methoxy-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

(5R,7S,8R,9R,10S)-7-(3-(4-ethylbenzyl)-4-methylphenyl)-1,6-dioxaspiro[4.5]decane-8,9,10-triol

US9034921, E187

(6S,7R,8R,9S)-6-(3-(4-ethylbenzyl)-4-methylphenyl)-2,5-dioxaspiro[3.5]nonane-7,8,9-triol

(6S,7R,8R,9S)-6-(3-(4-methoxybenzyl)-4-methylphenyl)-2,5-dioxaspiro[3.5]nonane-7,8,9-triol

4-((5-(4-chlorobenzylthio)-4-isopropyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one

US9034921, E024

US9315438, Reference compound 1

7-bromo-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

US9315438, Compound represented by formula (III)

(3S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-5-[(4-methylphenyl)methyl]spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

7-chloro-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

(1R,2S,3R,4R,6R)-4-[2-[(4-ethenylphenyl)methyl]phenoxy]-6-(hydroxymethyl)cyclohexane-1,2,3-triol

4-((5-(4-chlorobenzylthio)-4-phenyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one

(1R,2S,3R,4R,6R)-4-(hydroxymethyl)-6-[2-[(4-methylsulfanylphenyl)methyl]phenoxy]cyclohexane-1,2,3-triol

4-((5-(4-chlorobenzylthio)-4-cyclopropyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one

4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one

(1R,2S,3R,4R,6R)-4-[2-[(4-ethylphenyl)methyl]phenoxy]-6-(hydroxymethyl)cyclohexane-1,2,3-triol

US9034921, E181

(3S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-5-[(4-hydroxyphenyl)methyl]spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

(3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)-6-phenylspiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

(3S,3'R,4'S,5'S,6'R)-5-[(4-cyclopropylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

6-bromo-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

(6S,7R,8R,9S)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2,5-dioxaspiro[3.5]nonane-7,8,9-triol

(1R,2S,3R,4R,6R)-4-[2-[(4-cyclopropylphenyl)methyl]phenoxy]-6-(hydroxymethyl)cyclohexane-1,2,3-triol

4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-6-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one

(3S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-5-[(4-methylsulfanylphenyl)methyl]spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

(3S,3'R,4'S,5'S,6'R)-5-[(4-chlorophenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

US9034921, E194

6,8-dichloro-4-((5-(4-chlorophenethyl)-4-(3,3,3-trifluoropropyl)-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

(1R,2S,3R,4R,6R)-4-(hydroxymethyl)-6-[2-[(4-methylphenyl)methyl]phenoxy]cyclohexane-1,2,3-triol

(3S,4R,5R,6S)-6-(4-chloro-3-(4-methoxybenzyl)phenyl)-2,2-bis(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

6-chloro-4-((5-(4-chlorophenethyl)-4-isobutyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]thiazin-3(4H)-one

4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-6-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one

6-chloro-4-((5-(4-chlorophenethyl)-4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

6-chloro-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

8-chloro-4-((5-(4-chlorobenzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

(1R,2S,3R,4R,6R)-4-(hydroxymethyl)-6-[2-[(4-propylphenyl)methyl]phenoxy]cyclohexane-1,2,3-triol

TOFOGLIFLOZIN

(3S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-5-[(4-methoxyphenyl)methyl]spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

6,8-dichloro-4-((5-(4-chlorophenethyl)-4-propyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

(1R,2S,3R,4R,6R)-4-(hydroxymethyl)-6-[2-[(4-methoxyphenyl)methyl]phenoxy]cyclohexane-1,2,3-triol

4-((5-(4-chlorophenethyl)-4-propyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

US9034921, E233

(6S,7R,8R,9S)-6-(3-(4-ethylbenzyl)-4-methylphenyl)-5-oxa-2-azaspiro[3.5]nonane-7,8,9-triol

(6S,7R,8R,9S)-6-[3-(4-Ethyl-benzyl)-4-methyl-phenyl]-2,2-dioxo-5-oxa-2lambda*6*-thia-spiro[3.5]nonane-7,8,9-triol

(1S,2S,3S,4S,5S)-5-[4-Chloro-3-(4-methoxybenzyl)-phenyl]-1-(hydroxymethyl)-6,8-dioxa-bicyclo[3.2.1]octane-2,3,4-triol

(1S,2S,3S,4S,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)-phenyl]-1-(hydroxymethyl)-6,8-dioxa-bicyclo[3.2.1]octane-2,3,4-triol

4-((4-butyl-5-(4-chlorophenethyl)-4H-1,2,4-triazol-3-yl)methyl)-6-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one

(3S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-5-[(4-propan-2-ylphenyl)methyl]spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

(1R,2S,3R,4R,6R)-4-(2-benzylphenoxy)-6-(hydroxymethyl)cyclohexane-1,2,3-triol

(3S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-5-[(4-propylphenyl)methyl]spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

6-chloro-4-((5-(4-chlorophenethyl)-4-propyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

6-chloro-4-((5-(4-chlorophenethyl)-4-(3,3,3-trifluoropropyl)-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

US9315438, Compound represented by formula (II)

(3S,3'R,4'S,5'S,6'R)-5-[(4-fluorophenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

(1S,3'R,4'S,5'S,6'R)-6-(4-ethoxybenzyl)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triol

(1R,2S,3R,4R,6R)-4-(hydroxymethyl)-6-[2-[(4-hydroxyphenyl)methyl]phenoxy]cyclohexane-1,2,3-triol

(1R,2S,3R,4R,6R)-4-(hydroxymethyl)-6-[2-[(4-propan-2-ylphenyl)methyl]phenoxy]cyclohexane-1,2,3-triol

(1R,2S,3R,4R,6R)-4-[2-[(4-chlorophenyl)methyl]phenoxy]-6-(hydroxymethyl)cyclohexane-1,2,3-triol

Sergliflozin

(3S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-5-[[4-(trifluoromethyl)phenyl]methyl]spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

6-chloro-4-((5-(4-chlorophenethyl)-4-cyclopropyl-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

(3S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-5-[[4-(trifluoromethoxy)phenyl]methyl]spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol

(1R,2S,3R,4R,6R)-4-[2-[(4-fluorophenyl)methyl]phenoxy]-6-(hydroxymethyl)cyclohexane-1,2,3-triol

(1R,2S,3R,4R,6R)-4-[2-[(4-ethoxyphenyl)methyl]phenoxy]-6-(hydroxymethyl)cyclohexane-1,2,3-triol

4-((5-(4-chlorophenethyl)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

(1R,2S,3R,4R,6R)-4-(hydroxymethyl)-6-[2-[[4-(trifluoromethyl)phenyl]methyl]phenoxy]cyclohexane-1,2,3-triol

US9315438, Compound represented by formula (V)

4-[[(3S,3'R,4'S,5'S,6'R)-3',4',5'-trihydroxy-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-5-yl]methyl]benzonitrile

(6S,7R,8R,9S)-6-(4-chloro-3-(4-methoxybenzyl)phenyl)-2,5-dioxaspiro[3.5]nonane-7,8,9-triol