Brief Information of the Cell Line and Protein
Cell Line ID: CL000996 , RT-4
Synonyms
RT4
RT4P
Category Cancer cell line
Organism
Homo sapiens (Human)
Protein ID: PT03632 , Sigma intracellular receptor 2
Gene Name TMEM97
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q5BJF2
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000996  Protein ID: PT03632
 
Compound ID Compound Name Compound Formula
CP0521407
CHEMBL4454365
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C22H31NO
 1
1
Ki = 4.6 nM
   TI
   LI
   LO
   TS
CP0521410
N-(cyclohexylmethyl)-N-methylspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
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C22H33NO
 1
1
Ki = 5.5 nM
   TI
   LI
   LO
   TS
CP0562503
N-(cyclohexylmethyl)spiro[cyclohexane-4,1'-isochromene]-1-amine
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C21H29NO
 1
1
Ki = 6.7 nM
   TI
   LI
   LO
   TS
CP0562502
N-(cyclohexylmethyl)spiro[cyclohexane-4,1'-isochromene]-1-amine
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C21H29NO
 1
1
Ki = 7 nM
   TI
   LI
   LO
   TS
CP0565187
N-(cyclohexylmethyl)-1-methoxy-N-methylspiro[1H-2-benzofuran-3,4'-cyclohexane]-1'-amine
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C22H33NO2
 1
1
Ki = 7.6 nM
   TI
   LI
   LO
   TS
CP0535820
N-(cyclohexylmethyl)spiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
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C21H31NO
 1
1
Ki = 8 nM
   TI
   LI
   LO
   TS
CP0535819
CHEMBL4463331
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C22H33NO2
 1
1
Ki = 9.4 nM
   TI
   LI
   LO
   TS
CP0521408
N-(cyclohexylmethyl)-1-methoxyspiro[1H-2-benzofuran-3,4'-cyclohexane]-1'-amine
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C21H31NO2
 1
1
Ki = 11 nM
   TI
   LI
   LO
   TS
CP0459369
CHEMBL4467945
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C22H33NO
 1
1
Ki = 12 nM
   TI
   LI
   LO
   TS
CP0254828
N-(cyclohexylmethyl)-3-methoxy-N-methylspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
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C23H35NO2
 1
1
Ki = 13 nM
   TI
   LI
   LO
   TS
CP0541718
N-(cyclohexylmethyl)-3-ethoxy-N-methylspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
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C24H37NO2
 1
1
Ki = 14 nM
   TI
   LI
   LO
   TS
CP0521406
N-(cyclohexylmethyl)-N-methylspiro[cyclohexane-4,1'-isochromene]-1-amine
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C22H31NO
 1
1
Ki = 16 nM
   TI
   LI
   LO
   TS
CP0565186
N-(cyclohexylmethyl)-3-ethoxyspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
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C23H35NO2
 1
1
Ki = 16 nM
   TI
   LI
   LO
   TS
CP0013421
CAS_97-39-2
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C15H17N3
 1
1
Ki = 20 nM
   TI
   LI
   LO
   TS
CP0521409
N-(cyclohexylmethyl)spiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C21H31NO
 1
1
Ki = 33 nM
   TI
   LI
   LO
   TS
CP0541719
N-(cyclohexylmethyl)-1-methoxyspiro[1H-2-benzofuran-3,4'-cyclohexane]-1'-amine
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C21H31NO2
 1
1
Ki = 39 nM
   TI
   LI
   LO
   TS
CP0557767
N-(cyclohexylmethyl)-3-ethoxyspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
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C23H35NO2
 1
1
Ki = 46 nM
   TI
   LI
   LO
   TS
CP0489731
N-(cyclohexylmethyl)-3-ethoxy-N-methylspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
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C24H37NO2
 1
1
Ki = 93 nM
   TI
   LI
   LO
   TS
CP0535821
N-benzyl-3-methoxyspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
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C22H27NO2
 1
1
Ki = 227 nM
   TI
   LI
   LO
   TS