General Information of the Cell Line
Cell Line ID
CL000996
Cell Line Name
RT-4
Synonyms
RT4
RT4P
Category
Cancer cell line
Organism
Homo sapiens (Human)
Tissue Information
Urinary bladder
Disease
Bladder carcinoma (NCIt: C4912)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT03632, Sigma intracellular receptor 2
 Protein Info 
Compound ID Compound Name Compound Formula
CP0521407
 Compound Info 
CHEMBL4454365
   Show/Hide
C22H31NO
  1
1
Ki = 4.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0521410
 Compound Info 
N-(cyclohexylmethyl)-N-methylspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C22H33NO
  1
1
Ki = 5.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0562503
 Compound Info 
N-(cyclohexylmethyl)spiro[cyclohexane-4,1'-isochromene]-1-amine
   Show/Hide
C21H29NO
  1
1
Ki = 6.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0562502
 Compound Info 
N-(cyclohexylmethyl)spiro[cyclohexane-4,1'-isochromene]-1-amine
   Show/Hide
C21H29NO
  1
1
Ki = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0565187
 Compound Info 
N-(cyclohexylmethyl)-1-methoxy-N-methylspiro[1H-2-benzofuran-3,4'-cyclohexane]-1'-amine
   Show/Hide
C22H33NO2
  1
1
Ki = 7.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0535820
 Compound Info 
N-(cyclohexylmethyl)spiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C21H31NO
  1
1
Ki = 8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0535819
 Compound Info 
CHEMBL4463331
   Show/Hide
C22H33NO2
  1
1
Ki = 9.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0521408
 Compound Info 
N-(cyclohexylmethyl)-1-methoxyspiro[1H-2-benzofuran-3,4'-cyclohexane]-1'-amine
   Show/Hide
C21H31NO2
  1
1
Ki = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0459369
 Compound Info 
CHEMBL4467945
   Show/Hide
C22H33NO
  1
1
Ki = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0254828
 Compound Info 
N-(cyclohexylmethyl)-3-methoxy-N-methylspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C23H35NO2
  1
1
Ki = 13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0541718
 Compound Info 
N-(cyclohexylmethyl)-3-ethoxy-N-methylspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C24H37NO2
  1
1
Ki = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0521406
 Compound Info 
N-(cyclohexylmethyl)-N-methylspiro[cyclohexane-4,1'-isochromene]-1-amine
   Show/Hide
C22H31NO
  1
1
Ki = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0565186
 Compound Info 
N-(cyclohexylmethyl)-3-ethoxyspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C23H35NO2
  1
1
Ki = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0013421
 Compound Info 
CAS_97-39-2
   Show/Hide
C15H17N3
  1
1
Ki = 20 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0521409
 Compound Info 
N-(cyclohexylmethyl)spiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C21H31NO
  1
1
Ki = 33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0541719
 Compound Info 
N-(cyclohexylmethyl)-1-methoxyspiro[1H-2-benzofuran-3,4'-cyclohexane]-1'-amine
   Show/Hide
C21H31NO2
  1
1
Ki = 39 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557767
 Compound Info 
N-(cyclohexylmethyl)-3-ethoxyspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C23H35NO2
  1
1
Ki = 46 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0489731
 Compound Info 
N-(cyclohexylmethyl)-3-ethoxy-N-methylspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C24H37NO2
  1
1
Ki = 93 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0535821
 Compound Info 
N-benzyl-3-methoxyspiro[3,4-dihydroisochromene-1,4'-cyclohexane]-1'-amine
   Show/Hide
C22H27NO2
  1
1
Ki = 227 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0112599
 Compound Info 
US8569511, 2
   Show/Hide
 C23H22F2N6O2  1
1
IC50 = 1010 nM
   TI
   LI
   LO
   TS
CP0661487
 Compound Info 
3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea monophosphate
   Show/Hide
 C26H34Cl2N7O7P  1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Urinary bladder)
Cell Line Name Organism Disease
T24
 Cell Line Info 
Homo sapiens (Human) Bladder carcinoma
RT-112
 Cell Line Info 
Homo sapiens (Human) Bladder carcinoma
ECV-304
 Cell Line Info 
Homo sapiens (Human) Bladder carcinoma
UM-UC-3
 Cell Line Info 
Homo sapiens (Human) Bladder carcinoma
RT112/84-FABP4
 Cell Line Info 
Homo sapiens (Human) Bladder carcinoma