Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
 Cell Line Info 
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT03555 , Prostaglandin E2 receptor EP3 subtype
 Protein Info 
Gene Name PTGER3
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P34980
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043
 Cell Line Info 
 Protein ID: PT03555
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0459281
 Compound Info 
5-[6-(8-fluoronaphthalen-2-yl)-2-oxo-1H-pyridin-3-yl]-5-propan-2-yl-1,3-oxazolidine-2,4-dione
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C21H17FN2O4
  1
1
Ki = 3.162 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0459282
 Compound Info 
5-[6-(1-methylindol-5-yl)-2-oxo-1H-pyridin-3-yl]-5-propan-2-yl-1,3-oxazolidine-2,4-dione
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C20H19N3O4
  1
1
Ki = 7.943 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0073581
 Compound Info 
5-(6-naphthalen-2-yl-2-oxo-1H-pyridin-3-yl)-5-propan-2-yl-1,3-oxazolidine-2,4-dione
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C21H18N2O4
  1
1
Ki = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0494626
 Compound Info 
5-[6-(3,4-dimethylphenyl)-2-oxo-1H-pyridin-3-yl]-5-propan-2-yl-1,3-oxazolidine-2,4-dione
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C19H20N2O4
  1
1
Ki = 12.59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0875714
 Compound Info 
5-[6-(2-naphthalenyl)-2-oxo-1,2-dihydro-3-pyridinyl]-1,3-oxazolidine-2,4-dione
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C18H12N2O4
  1
1
Ki = 316.23 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS