Brief Information of the Cell Line and Protein
Cell Line ID: CL000410 , SJSA-1
Synonyms
SJSA1
SJSA
OsA-CL
OSA-CL
OsACL
OSACL
Os-A
OSA
OsA
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1697
Protein ID: PT03225 , Cellular tumor antigen p53
Gene Name TP53
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P04637
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000410  Protein ID: PT03225
 
Compound ID Compound Name Compound Formula
CP0073355
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S,3S)-2-hydroxypentan-3-yl]-3-methyl-2-oxopiperidin-3-yl]acetic acid
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C25H29Cl2NO4
 1
1
IC50 = 760 nM
   TI
   LI
   LO
   TS
CP0543287
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S)-1-hydroxybutan-2-yl]-3-methyl-2-oxopiperidin-3-yl]acetic acid
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C24H27Cl2NO4
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0076255
tert-butyl (2S)-2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxo-3-(2H-tetrazol-5-ylmethyl)piperidin-1-yl]butanoate
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C28H33Cl2N5O3
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0246368
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(2S)-1-[(2-methylpropan-2-yl)oxy]-1-oxobutan-2-yl]-2-oxopiperidin-3-yl]acetic acid
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C28H33Cl2NO5
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0480920
tert-butyl (2S)-2-[(2S,3R,5R)-3-(3-chlorophenyl)-2-(4-chlorophenyl)-6-oxo-5-(2H-tetrazol-5-ylmethyl)piperidin-1-yl]butanoate
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C27H31Cl2N5O3
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0543288
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S)-1-[(2-methylpropan-2-yl)oxy]-1-oxobutan-2-yl]-2-oxopiperidin-3-yl]acetic acid
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C27H31Cl2NO5
 1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS
CP0507199
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxo-1-pentan-3-ylpiperidin-3-yl]acetic acid
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C25H29Cl2NO3
 1
1
IC50 = 5500 nM
   TI
   LI
   LO
   TS
CP0041876
(4S,5R)-Nutlin-3
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C30H30Cl2N4O4
 1
1
IC50 = 7100 nM
   TI
   LI
   LO
   TS
CP0491289
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S)-1-ethoxy-1-oxobutan-2-yl]-2-oxopiperidin-3-yl]acetic acid
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C25H27Cl2NO5
 1
1
IC50 = 10700 nM
   TI
   LI
   LO
   TS
CP0141684
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(cyclopropylmethyl)-2-oxopiperidin-3-yl]acetic acid
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C23H23Cl2NO3
 1
1
IC50 = 34400 nM
   TI
   LI
   LO
   TS