Brief Information of the Compound and Protein
Compound Name
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(2S)-1-[(2-methylpropan-2-yl)oxy]-1-oxobutan-2-yl]-2-oxopiperidin-3-yl]acetic acid
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PubChem ID
CID: 56591154
SID: 134218403
Canonical SMILES
CC[C@H](N1[C@@H]([C@H](C[C@](C)(CC(O)=O)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1)C(=O)OC(C)(C)C
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Compound Formula C28H33Cl2NO5
Compound Structure
Protein Name
Cellular tumor antigen p53
Protein Classification
Transcription factor
Uniprot ID
P04637
Gene Name
TP53
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CL000410 SJSA-1 Homo sapiens (Human)  1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS