Brief Information of the Cell Line and Protein
Cell Line ID: CL000530 , OCI-Ly19
 Cell Line Info 
Synonyms
OCI-LY19
OCI-LY-19
OCI-Ly 19
OCI Ly19
OCILY-19
OCILY19
OCILy19
Ly19
LY19
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1878
Protein ID: PT03193 , Polycomb protein EED
 Protein Info 
Gene Name EED
Organism Homo sapiens, Human
Protein Classification Unclassified protein
Uniprot ID O75530
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000530
 Cell Line Info 
 Protein ID: PT03193
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0103693
 Compound Info 
(1S,2R)-4-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-2-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]cyclopentan-1-amine
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C27H36FN3O2S
  1
1
IC50 = 44 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0226502
 Compound Info 
1-[4-[4-[(3S,4R)-4-(dimethylamino)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)pyrrolidin-3-yl]phenyl]piperazin-1-yl]ethanone
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C27H35FN4O
  1
1
IC50 = 50 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0103694
 Compound Info 
4-[3-[(3S,4R)-4-(dimethylamino)-1-[(2-fluoro-6-methylphenyl)methyl]pyrrolidin-3-yl]-1-methylindol-7-yl]-1-methylpiperazin-2-one
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C28H36FN5O
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0477678
 Compound Info 
[3-[(3S,4R)-4-(dimethylamino)-1-[(2-fluoro-6-methylphenyl)methyl]pyrrolidin-3-yl]-1-methylindol-7-yl]-(3-fluoroazetidin-1-yl)methanone
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C27H32F2N4O
  1
1
IC50 = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0561455
 Compound Info 
6-[4-[(3S,4R)-4-(dimethylamino)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)pyrrolidin-3-yl]piperidin-1-yl]pyridine-3-carboxamide
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C26H34FN5O
  1
1
IC50 = 280 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0365496
 Compound Info 
(3R,4S)-1-[(1S)-7-fluoroindan-1-yl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine (3)
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C24H28FN3
  1
1
IC50 = 660 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0226498
 Compound Info 
rac-(3R,4S)-1-(2-fluoro-6-methylbenzyl)-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine (2)
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C23H28FN3
  1
1
IC50 = 2400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0226501
 Compound Info 
(3R,4S)-1-[(2-bromo-6-fluorophenyl)methyl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine
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C22H25BrFN3
  1
1
IC50 = 8300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393488
 Compound Info 
(3R,4S)-1-[(2-chloro-6-fluorophenyl)methyl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine
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C22H25ClFN3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS