Brief Information of the Compound and Protein
Compound Name
6-[4-[(3S,4R)-4-(dimethylamino)-1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)pyrrolidin-3-yl]piperidin-1-yl]pyridine-3-carboxamide
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PubChem ID
CID: 132085570
Canonical SMILES
CN(C)[C@H]1CN(C[C@@H]1C1CCN(CC1)c1ccc(cn1)C(N)=O)C1CCc2cccc(F)c12
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Compound Formula C26H34FN5O
Compound Structure
Protein Name
Polycomb protein EED
Protein Classification
Unclassified protein
Uniprot ID
O75530
Gene Name
EED
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000175 G-401 Homo sapiens (Human)  1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS
CL000530 OCI-Ly19 Homo sapiens (Human)  1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.45 nM