Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R,4S)-1-[(2-bromo-6-fluorophenyl)methyl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine
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 PubChem ID
CID: 124220776
Canonical SMILES
CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1c1cn(C)c2ccccc12
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Compound Formula C22H25BrFN3
Compound Structure
Protein Name
 Protein Info 
Polycomb protein EED
Protein Classification
Unclassified protein
Uniprot ID
O75530
Gene Name
EED
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000175 G-401
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4100 nM
   TI
   LI
   LO
   TS
CL000530 OCI-Ly19
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 150 nM
2 Ki = 10 nM
3 Ki = 13 nM