Brief Information of the Cell Line and Protein
Cell Line ID: CL000187 , Calu-6
 Cell Line Info 
Synonyms
CaLu-6
CALU-6
Calu.6
Calu 6
Calu6
CALU6
CaLu-06
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0236
Protein ID: PT03087 , Protein arginine N-methyltransferase 5
 Protein Info 
Gene Name PRMT5
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID O14744
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000187
 Cell Line Info 
 Protein ID: PT03087
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0568549
 Compound Info 
3-[(2-amino-3-methylquinolin-7-yl)methyl]-N-methyl-2-oxo-N-phenyl-1,3-oxazole-4-carboxamide
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C22H20N4O3
  1
1
IC50 = 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0546124
 Compound Info 
3-[(2-amino-3-methylquinolin-7-yl)methyl]-N,1-dimethyl-2-oxo-N-phenylimidazole-4-carboxamide
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C23H23N5O2
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0572941
 Compound Info 
4-[(2-amino-3-methylquinolin-7-yl)methyl]-N,1-dimethyl-5-oxo-N-phenyl-1,2,4-triazole-3-carboxamide
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C22H22N6O2
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0571008
 Compound Info 
3-[(2-amino-3-methylquinolin-7-yl)methyl]-N,1-dimethyl-2-oxo-N-pyridin-2-ylimidazole-4-carboxamide
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C22H22N6O2
  1
1
IC50 = 9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568520
 Compound Info 
2-[(2-amino-3-methylquinolin-7-yl)methyl]-N-(3-fluoropyridin-2-yl)-N-methylpyrazole-3-carboxamide
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C21H19FN6O
  1
1
IC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578499
 Compound Info 
1-[(2-amino-3-methylquinolin-7-yl)methyl]-N-methyl-6-oxo-N-phenylpyridine-2-carboxamide
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C24H22N4O2
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0577191
 Compound Info 
4-[(2-amino-3-methylquinolin-7-yl)methyl]-N,1-dimethyl-5-oxo-N-pyridin-2-yl-1,2,4-triazole-3-carboxamide
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C21H21N7O2
  1
1
IC50 = 21 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0575005
 Compound Info 
3-[(6-amino-7-methyl-1,5-naphthyridin-3-yl)methyl]-N,1-dimethyl-2-oxo-N-phenylimidazole-4-carboxamide
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C22H22N6O2
  1
1
IC50 = 29 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570820
 Compound Info 
1-[(2-amino-3-methylquinolin-7-yl)methyl]-N-methyl-6-oxo-N-phenylpyrimidine-2-carboxamide
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C23H21N5O2
  1
1
IC50 = 39 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568033
 Compound Info 
4-[(2-amino-3-methylquinolin-7-yl)methyl]-N-methyl-5-oxo-N-phenyl-1,2,4-oxadiazole-3-carboxamide
   Show/Hide
C21H19N5O3
  1
1
IC50 = 49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570821
 Compound Info 
3-[(2-amino-3-methylquinolin-7-yl)methyl]-N-methyl-N-phenyltriazole-4-carboxamide
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C21H20N6O
  1
1
IC50 = 50 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS