| Compound ID |
Compound Name |
Compound Formula |
|
CP0223870
|
CHEMBL3741505
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|
C22H22N4O4S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0223869
|
CHEMBL3739742
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|
C21H26N4O4S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0400124
|
2-[4-[4-[[5-(2-cyclopentylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C24H31N3O3S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0070794
|
CHEMBL3741095
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|
C23H21F2N3O4S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0448175
|
CHEMBL3741333
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|
C22H27N3O5S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0149070
|
4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenoxy]cyclohexane-1-carboxylic acid
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|
C23H23N3O4S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0235312
|
2-[4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C24H25N3O3S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0530183
|
2-[4-[4-[[5-(cyclopentylmethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C23H29N3O3S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0525068
|
2-[4-[4-[[5-[(2-fluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C24H24FN3O3S
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0430761
|
2-[4-[4-[[5-[(3-fluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C24H24FN3O3S
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0525067
|
CHEMBL2012631
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|
C24H24ClN3O3S
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0313000
|
CHEMBL3740753
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|
C23H29N3O4S
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0573784
|
CHEMBL3741896
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|
C23H21F2N3O4S
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0531336
|
4-[5-[[5-[(3-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]pyridin-2-yl]oxycyclohexane-1-carboxylic acid
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|
C22H21ClN4O4S
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0430753
|
2-[4-[4-[[5-[(4-fluorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C24H24FN3O4S
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0430763
|
2-[4-[4-[[5-(2-cyclobutylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C23H29N3O3S
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0400125
|
2-[4-[4-[[5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C24H25N3O4S
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0313002
|
2-[4-[4-[[5-[(4-fluorophenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C24H24FN3O3S
|
2
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
IC50 = 131 nM
|
|
|
|
CP0083969
|
4-[5-[(5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl]pyridin-2-yl]oxycyclohexane-1-carboxylic acid
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|
C22H22N4O4S
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0522514
|
2-[4-[4-[[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C25H27N3O4S
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0400126
|
2-[4-[4-[[5-[2-(4-fluorophenyl)ethyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C25H26FN3O3S
|
1
|
| 1 |
IC50 = 173 nM
|
|
|
|
CP0430762
|
2-[4-[4-[[5-[3-(4-fluorophenyl)propyl]-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C26H28FN3O3S
|
1
|
| 1 |
IC50 = 181 nM
|
|
|
|
CP0400128
|
(2S)-2-[[4-[4-[(5-benzyl-1,3,4-thiadiazol-2-yl)amino]phenyl]benzoyl]amino]-3-methylbutanoic acid
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|
C27H26N4O3S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0531337
|
CHEMBL3741016
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|
C23H21F2N3O5
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0430755
|
2-[4-[4-[(5-phenyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl]cyclohexyl]acetic acid
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|
C23H23N3O3S
|
1
|
| 1 |
IC50 = 588 nM
|
|
|
|
CP0400131
|
2-[4-[4-[[5-(2-phenylethyl)-1,3,4-thiadiazol-2-yl]carbamoyl]phenyl]cyclohexyl]acetic acid
Show/Hide
|
C25H27N3O3S
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
