| Compound ID |
Compound Name |
Compound Formula |
|
CP0221365
|
(R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)piperidine-3-carboxylic acid hydrochloride
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|
C20H25NO2S2
|
3
|
| 1 |
IC50 = 380.19 nM
|
|
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| 2 |
Ki = 16.98 nM
|
|
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| 3 |
Ki = 47.86 nM
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CP0397783
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(2S)-2-[(2R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl]pyrrolidin-2-yl]-2-hydroxyacetic acid
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|
C20H25NO3S2
|
2
|
| 1 |
IC50 = 724.44 nM
|
|
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| 2 |
Ki = 66.07 nM
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CP0379824
|
(2S)-2-[(2R)-1-(4,4-diphenylbut-3-enyl)pyrrolidin-2-yl]-2-hydroxyacetic acid
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|
C22H25NO3
|
2
|
| 1 |
IC50 = 1905.46 nM
|
|
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| 2 |
Ki = 213.8 nM
|
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CP0411793
|
(2R)-2-[(2R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl]pyrrolidin-2-yl]-2-hydroxyacetic acid
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|
C20H25NO3S2
|
2
|
| 1 |
IC50 = 4168.69 nM
|
|
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| 2 |
Ki = 1096.48 nM
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CP0397774
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(2R)-2-[(2R)-1-(4,4-diphenylbut-3-enyl)pyrrolidin-2-yl]-2-hydroxyacetic acid
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|
C22H25NO3
|
2
|
| 1 |
IC50 = 13803.84 nM
|
|
|
| 2 |
Ki = 3981.07 nM
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CP0053588
|
(R,E)-1-(4-(2-fluorophenyl)-4-o-tolylbut-3-enyl)piperidine-3-carboxylic acid
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|
C23H26FNO2
|
1
|
| 1 |
Ki = 14.79 nM
|
|
|
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CP0427463
|
(3R)-1-[(Z)-4-(2-chlorophenyl)-4-(2-fluorophenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C22H23ClFNO2
|
1
|
| 1 |
Ki = 18.2 nM
|
|
|
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CP0505337
|
(3R)-1-[(E)-4-(4-fluoro-2-methylphenyl)-4-(2-fluorophenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C23H25F2NO2
|
1
|
| 1 |
Ki = 19.05 nM
|
|
|
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CP0506041
|
(3R)-1-[(Z)-4-(2-methylphenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C23H27NO2
|
1
|
| 1 |
Ki = 20.42 nM
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CP0500547
|
(3R)-1-[(Z)-4-(2-bromophenyl)-4-(2-fluorophenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C22H23BrFNO2
|
1
|
| 1 |
Ki = 21.88 nM
|
|
|
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CP0516537
|
(3R)-1-[(Z)-4-(2-bromophenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C22H24BrNO2
|
1
|
| 1 |
Ki = 28.84 nM
|
|
|
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CP0477206
|
(3R)-1-[(Z)-4-(2-ethylphenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C24H29NO2
|
1
|
| 1 |
Ki = 29.51 nM
|
|
|
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CP0471644
|
(3R)-1-[(Z)-4-(4-fluoro-2-methylphenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C23H26FNO2
|
1
|
| 1 |
Ki = 33.88 nM
|
|
|
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CP0514873
|
(3R)-1-[(E)-4-(2-ethylphenyl)-4-(2-fluorophenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C24H28FNO2
|
1
|
| 1 |
Ki = 38.02 nM
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CP0506042
|
(3R)-1-[(E)-4-(4-fluoro-2-methylphenyl)-4-[2-(trifluoromethyl)phenyl]but-3-enyl]piperidine-3-carboxylic acid
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|
C24H25F4NO2
|
1
|
| 1 |
Ki = 38.9 nM
|
|
|
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CP0379684
|
(3R)-1-[(Z)-4-(2-chlorophenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C22H24ClNO2
|
1
|
| 1 |
Ki = 40.74 nM
|
|
|
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CP0379688
|
(3R)-1-[4,4-bis(2-methylphenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C24H29NO2
|
1
|
| 1 |
Ki = 41.69 nM
|
|
|
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CP0471645
|
(3R)-1-[4,4-bis(2-fluorophenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C22H23F2NO2
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
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CP0505336
|
(3R)-1-[(E)-4-(2-fluorophenyl)-4-[2-(trifluoromethoxy)phenyl]but-3-enyl]piperidine-3-carboxylic acid
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|
C23H23F4NO3
|
1
|
| 1 |
Ki = 52.48 nM
|
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|
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CP0514874
|
(3R)-1-[(E)-4-(2-fluorophenyl)-4-(2-methoxyphenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C23H26FNO3
|
1
|
| 1 |
Ki = 53.7 nM
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CP0505335
|
(3R)-1-[(Z)-4-(2-methoxyphenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C23H27NO3
|
1
|
| 1 |
Ki = 56.23 nM
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CP0379685
|
(3R)-1-[(Z)-4-phenyl-4-[2-(trifluoromethoxy)phenyl]but-3-enyl]piperidine-3-carboxylic acid
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|
C23H24F3NO3
|
1
|
| 1 |
Ki = 58.88 nM
|
|
|
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CP0425724
|
(3R)-1-[(E)-4-(2-chlorophenyl)-4-(2-methylphenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C23H26ClNO2
|
1
|
| 1 |
Ki = 61.66 nM
|
|
|
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CP0538819
|
(3R)-1-[(Z)-4-(2-fluorophenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C22H24FNO2
|
1
|
| 1 |
Ki = 69.18 nM
|
|
|
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CP0487274
|
(3R)-1-[(E)-4-(2-methoxyphenyl)-4-(2-methylphenyl)but-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C24H29NO3
|
1
|
| 1 |
Ki = 70.79 nM
|
|
|
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CP0043916
|
(R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxylic acid
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|
C22H25NO2
|
1
|
| 1 |
Ki = 72.44 nM
|
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|
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CP0379687
|
(3R)-1-[(Z)-4-(2-fluorophenyl)-4-(2-methylphenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C23H26FNO2
|
1
|
| 1 |
Ki = 72.44 nM
|
|
|
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CP0379686
|
(3R)-1-[(Z)-4-(2,6-dimethylphenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C24H29NO2
|
1
|
| 1 |
Ki = 77.62 nM
|
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CP0549834
|
(3R)-1-[(Z)-4-(2-ethylphenyl)-4-(2-fluorophenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C24H28FNO2
|
1
|
| 1 |
Ki = 89.13 nM
|
|
|
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CP0503778
|
(3R)-1-[(Z)-4-phenyl-4-[2-(trifluoromethyl)phenyl]but-3-enyl]piperidine-3-carboxylic acid
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|
C23H24F3NO2
|
1
|
| 1 |
Ki = 93.33 nM
|
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|
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CP0514871
|
(3R)-1-[(E)-4-(2-methylphenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C23H27NO2
|
1
|
| 1 |
Ki = 93.33 nM
|
|
|
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CP0503777
|
(3R)-1-[(E)-4-(2-ethylphenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C24H29NO2
|
1
|
| 1 |
Ki = 102.33 nM
|
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|
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CP0506043
|
1-[4,4-bis(5-methylthiophen-2-yl)but-3-enyl]-3-fluoropiperidine-3-carboxylic acid
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|
C20H24FNO2S2
|
1
|
| 1 |
Ki = 138.04 nM
|
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CP0549835
|
(3R)-1-[(E)-4-(2-chlorophenyl)-4-(2-fluorophenyl)but-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C22H23ClFNO2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
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CP0474399
|
(3R)-1-[(E)-4-(2-chlorophenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C22H24ClNO2
|
1
|
| 1 |
Ki = 165.96 nM
|
|
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CP0487273
|
(3R)-1-[(E)-4-(2-bromophenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C22H24BrNO2
|
1
|
| 1 |
Ki = 199.53 nM
|
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CP0477207
|
(3R)-1-[(Z)-4-(2,6-difluorophenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C22H23F2NO2
|
1
|
| 1 |
Ki = 331.13 nM
|
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CP0500545
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(3R)-1-[(Z)-4-(2-fluorophenyl)-4-[2-(trifluoromethyl)phenyl]but-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C23H23F4NO2
|
1
|
| 1 |
Ki = 354.81 nM
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CP0477205
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(3R)-1-[(E)-4-(2-methoxyphenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
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|
C23H27NO3
|
1
|
| 1 |
Ki = 371.54 nM
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CP0503776
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(3R)-1-[(E)-4-(2-fluorophenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C22H24FNO2
|
1
|
| 1 |
Ki = 371.54 nM
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CP0500546
|
(3R)-1-[(E)-4-(2-methylphenyl)-4-[2-(trifluoromethyl)phenyl]but-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C24H26F3NO2
|
1
|
| 1 |
Ki = 380.19 nM
|
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CP0549833
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(3R)-1-[(E)-4-(4-fluoro-2-methylphenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C23H26FNO2
|
1
|
| 1 |
Ki = 380.19 nM
|
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CP0427462
|
(3R)-1-[(E)-4-phenyl-4-[2-(trifluoromethoxy)phenyl]but-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C23H24F3NO3
|
1
|
| 1 |
Ki = 645.65 nM
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CP0511745
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(3R)-1-[(E)-4-phenyl-4-(2-phenylphenyl)but-3-enyl]piperidine-3-carboxylic acid
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|
C28H29NO2
|
1
|
| 1 |
Ki = 676.08 nM
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CP0514872
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(3R)-1-[(E)-4-(2,6-difluorophenyl)-4-phenylbut-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C22H23F2NO2
|
1
|
| 1 |
Ki = 691.83 nM
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CP0516538
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1-(4,4-diphenylbut-3-enyl)-3-fluoropiperidine-3-carboxylic acid
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|
C22H24FNO2
|
1
|
| 1 |
Ki = 831.76 nM
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CP0503779
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(3R)-1-[(Z)-4-phenyl-4-(2-phenylphenyl)but-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C28H29NO2
|
1
|
| 1 |
Ki = 1071.52 nM
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CP0516536
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(3R)-1-[(E)-4-phenyl-4-[2-(trifluoromethyl)phenyl]but-3-enyl]piperidine-3-carboxylic acid
Show/Hide
|
C23H24F3NO2
|
1
|
| 1 |
Ki = 1905.46 nM
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CP0379689
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1-[(1S,2R,5S)-8-(4,4-diphenylbut-3-enyl)-8-azabicyclo[3.2.1]octan-2-yl]ethanone
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|
C25H29NO
|
1
|
| 1 |
Ki = 2754.23 nM
|
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CP0379690
|
4-[4,4-bis(5-methylthiophen-2-yl)but-3-enyl]morpholine-2-carboxylic acid
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|
C19H23NO3S2
|
1
|
| 1 |
Ki > 10000 nM
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CP0477208
|
(1R,5S)-3-[4,4-bis(5-methylthiophen-2-yl)but-3-enyl]-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
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|
C20H23NO2S2
|
1
|
| 1 |
Ki > 10000 nM
|
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CP0477209
|
(1R,6S,7R)-3-[4,4-bis(5-methylthiophen-2-yl)but-3-enyl]-3-azabicyclo[4.1.0]heptane-7-carboxylic acid
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|
C21H25NO2S2
|
1
|
| 1 |
Ki > 10000 nM
|
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CP0487277
|
(1S,2S)-2-[4,4-bis(5-methylthiophen-2-yl)but-3-enyl-methylamino]cyclohexane-1-carboxylic acid
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|
C22H29NO2S2
|
1
|
| 1 |
Ki > 10000 nM
|
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CP0487278
|
(1S,6R,7R)-3-[4,4-bis(5-methylthiophen-2-yl)but-3-enyl]-3-azabicyclo[4.1.0]heptane-7-carboxylic acid
Show/Hide
|
C21H25NO2S2
|
1
|
| 1 |
Ki > 10000 nM
|
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CP0549836
|
(1S,2S)-2-[4,4-bis(5-methylthiophen-2-yl)but-3-enyl-methylamino]cyclopentane-1-carboxylic acid
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|
C21H27NO2S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0549837
|
(1R,5S)-3-[4,4-bis(5-methylthiophen-2-yl)but-3-enyl]-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
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|
C20H23NO2S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0848173
|
(2SR)-2-Amino-2-{(2RS)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl]pyrrolidine-2-yl}aceticacid ditrifluoroaceticacid
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|
C22H27F3N2O4S2
|
1
|
| 1 |
Ki = 19054.61 nM
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CP0858008
|
(2RS)-2-Amino-2-{(2RS)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl]-pyrrolidine-2-yl}aceticacid ditrifluoroaceticacid
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|
C22H27F3N2O4S2
|
1
|
| 1 |
Ki = 20417.38 nM
|
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