Brief Information of the Compound and Protein
Compound Name
(2R)-2-[(2R)-1-(4,4-diphenylbut-3-enyl)pyrrolidin-2-yl]-2-hydroxyacetic acid
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PubChem ID
CID: 118727501
Canonical SMILES
O[C@H]([C@H]1CCCN1CCC=C(c1ccccc1)c1ccccc1)C(O)=O
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Compound Formula C22H25NO3
Compound Structure
Protein Name
Sodium- and chloride-dependent GABA transporter 1
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P30531
Gene Name
SLC6A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 13803.84 nM
   TI
   LI
   LO
   TS
2
Ki = 3981.07 nM
   TI
   LI
   LO
   TS