Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
 Cell Line Info 
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT02455 , Glucose-dependent insulinotropic receptor
 Protein Info 
Gene Name GPR119
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q8TDV5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043
 Cell Line Info 
 Protein ID: PT02455
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0282904
 Compound Info 
2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]pyrazole-3-carbonitrile
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C23H24N10O
  1
1
EC50 = 5.32 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0310370
 Compound Info 
4-[(4-cyano-2-fluorophenoxy)methyl]-2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]pyrazole-3-carbonitrile
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C23H22FN7O
  1
1
EC50 = 5.36 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388345
 Compound Info 
(1-methylcyclopropyl) 4-[5-cyano-4-[[4-(tetrazol-1-yl)phenoxy]methyl]pyrazol-1-yl]piperidine-1-carboxylate
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C22H24N8O3
  1
1
EC50 = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0210924
 Compound Info 
(1-methylcyclopropyl) 4-[5-cyano-4-[(4-cyano-2-fluorophenoxy)methyl]pyrazol-1-yl]piperidine-1-carboxylate
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C22H22FN5O3
  1
1
EC50 = 30.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0210925
 Compound Info 
(1-methylcyclopropyl) 4-[5-cyano-4-[[2-fluoro-4-(1-methyltetrazol-5-yl)phenoxy]methyl]pyrazol-1-yl]piperidine-1-carboxylate
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C23H25FN8O3
  1
1
EC50 = 62.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS