| Compound ID |
Compound Name |
Compound Formula |
|
CP0135643
|
3-[(1R)-1-[[3-chloro-7-fluoro-6-[2-(2-hydroxypropan-2-yl)pyrimidin-5-yl]-2-methyl-1,5-naphthyridin-4-yl]amino]ethyl]-4-fluorobenzonitrile
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|
C25H21ClF2N6O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0563803
|
2-[5-[4-[[(1R)-1-(5-amino-2-fluorophenyl)ethyl]amino]-3-chloroquinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H23ClFN5O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
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CP0497254
|
3-[(1R)-1-[[3-chloro-6-[2-(2-hydroxypropan-2-yl)pyrimidin-5-yl]quinolin-4-yl]amino]ethyl]-4-fluorobenzonitrile
Show/Hide
|
C25H21ClFN5O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0557206
|
2-[5-[3-chloro-7-fluoro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H21ClF2N4O
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
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CP0564388
|
2-[4-[3-chloro-4-[[(1R)-1-(2-fluorophenyl)ethyl]amino]quinolin-6-yl]phenyl]propan-2-ol
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|
C26H24ClFN2O
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
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CP0315218
|
5-[3-chloro-4-(2,5-dimethylanilino)quinolin-6-yl]pyridine-2-carbonitrile
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|
C23H17ClN4
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
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CP0135686
|
2-[5-[3-chloro-4-(2,5-dimethylanilino)quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H23ClN4O
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0472975
|
2-[5-[4-(2,5-dimethylanilino)-3-methylquinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C25H26N4O
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0513634
|
2-[5-[3-chloro-4-[[(1R)-1-(2-fluorophenyl)ethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H22ClFN4O
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0513638
|
2-[4-[5-[3-chloro-4-[[(1R)-1-(2-fluorophenyl)ethyl]amino]quinolin-6-yl]pyrimidin-2-yl]piperazin-1-yl]acetic acid
Show/Hide
|
C27H26ClFN6O2
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0539915
|
3-chloro-6-[2-(1,1-dioxo-1,4-thiazinan-4-yl)pyrimidin-5-yl]-N-[(1R)-1-(2-fluorophenyl)ethyl]quinolin-4-amine
Show/Hide
|
C25H23ClFN5O2S
|
1
|
| 1 |
IC50 = 152 nM
|
|
|
|
CP0497255
|
2-[5-[3,7-dichloro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H21Cl2FN4O
|
1
|
| 1 |
IC50 = 178 nM
|
|
|
|
CP0539914
|
2-[5-[3-chloro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H22ClFN4O
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
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CP0315219
|
2-[5-[3-chloro-4-(2,5-dimethylanilino)-2-methylquinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C25H25ClN4O
|
1
|
| 1 |
IC50 = 196 nM
|
|
|
|
CP0190452
|
[1-[(2,5-dimethylphenyl)methyl]-6-(1-methylpyrazol-4-yl)benzimidazol-2-yl]-pyridin-4-ylmethanol
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|
C26H25N5O
|
1
|
| 1 |
IC50 = 202 nM
|
|
|
|
CP0557233
|
2-[5-[3-chloro-8-fluoro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H21ClF2N4O
|
1
|
| 1 |
IC50 = 224 nM
|
|
|
|
CP0421562
|
2-[5-[3-chloro-4-[[(1R)-1-(2-fluoro-5-pyrrolidin-1-ylphenyl)ethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C28H29ClFN5O
|
1
|
| 1 |
IC50 = 331 nM
|
|
|
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CP0513639
|
2-[5-[3,5-dichloro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H21Cl2FN4O
|
1
|
| 1 |
IC50 = 365 nM
|
|
|
|
CP0421561
|
2-[5-[3-chloro-4-[1-(2-fluorophenyl)propylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C25H24ClFN4O
|
1
|
| 1 |
IC50 = 368 nM
|
|
|
|
CP0557231
|
2-[5-[3-chloro-4-[1-[2-(trifluoromethyl)phenyl]ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C25H22ClF3N4O
|
1
|
| 1 |
IC50 = 407 nM
|
|
|
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CP0556953
|
2-[5-[3-chloro-4-[[(1R)-1-phenylethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H23ClN4O
|
1
|
| 1 |
IC50 = 496 nM
|
|
|
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CP0513637
|
3-chloro-6-(2-ethoxypyrimidin-5-yl)-N-[(1R)-1-(2-fluorophenyl)ethyl]quinolin-4-amine
Show/Hide
|
C23H20ClFN4O
|
1
|
| 1 |
IC50 = 587 nM
|
|
|
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CP0570382
|
2-[5-[3-chloro-4-[[1-(2-fluorophenyl)-2-methylpropyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C26H26ClFN4O
|
1
|
| 1 |
IC50 = 826 nM
|
|
|
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CP0472974
|
6-bromo-3-chloro-N-(2,5-dimethylphenyl)quinolin-4-amine
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|
C17H14BrClN2
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
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CP0513635
|
2-[5-[3-chloro-4-[1-(4-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H22ClFN4O
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
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CP0550414
|
3-chloro-N-[(1R)-1-(2-fluorophenyl)ethyl]-6-(6-methylsulfonylpyridin-3-yl)quinolin-4-amine
Show/Hide
|
C23H19ClFN3O2S
|
1
|
| 1 |
IC50 = 909 nM
|
|
|
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CP0568290
|
2-[5-[3-chloro-4-[1-(3-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H22ClFN4O
|
1
|
| 1 |
IC50 = 1037 nM
|
|
|
|
CP0135683
|
5-[4-(2,5-dimethylanilino)quinolin-6-yl]pyridine-2-carbonitrile
Show/Hide
|
C23H18N4
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
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CP0421560
|
2-[5-[3-chloro-4-[[(1S)-1-phenylethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H23ClN4O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
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CP0513633
|
2-[5-[4-(benzylamino)-3-chloroquinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C23H21ClN4O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
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CP0539913
|
2-[5-[3-chloro-4-(2-phenylpropan-2-ylamino)quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C25H25ClN4O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0550413
|
2-[5-[3-chloro-4-(1-pyridin-2-ylethylamino)quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C23H22ClN5O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
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CP0557232
|
2-[5-[3,8-dichloro-4-[1-(2-fluorophenyl)ethylamino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C24H21Cl2FN4O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
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CP0570383
|
2-[5-[4-[[(1R)-1-(2-fluoro-5-pyrrolidin-1-ylphenyl)ethyl]amino]quinolin-6-yl]pyrimidin-2-yl]propan-2-ol
Show/Hide
|
C28H30FN5O
|
1
|
| 1 |
IC50 > 25000 nM
|
|
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