| Compound ID |
Compound Name |
Compound Formula |
|
CP0410792
|
1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutane-1-carboxamide
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|
C25H20F6N4O4S
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0504219
|
2-methyl-2-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]propanamide
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|
C24H20F6N4O4S
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0385700
|
2-[3-[1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutyl]-1,2,4-oxadiazol-5-yl]propan-2-ol
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|
C29H25F6N5O5S
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
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CP0315938
|
[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]methanol
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|
C26H24F3N5O4S
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
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CP0315941
|
6-(4-tert-butylphenyl)sulfonyl-7-(1-methylpyrazol-4-yl)-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
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|
C27H26F3N5O2S
|
1
|
| 1 |
IC50 = 0.76 nM
|
|
|
|
CP0179883
|
2-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
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|
C28H28F3N5O4S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0191374
|
3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazole
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|
C25H22F3N5O3S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0110516
|
(1S)-1-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]ethanol
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|
C27H26F3N5O4S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0385699
|
2-[3-[2-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]propan-2-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
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|
C28H25F6N5O5S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0315773
|
6-(4-tert-butylphenyl)sulfonyl-7-piperidin-4-yl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
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|
C28H31F3N4O2S
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0085078
|
2-[3-[6-(4-propan-2-ylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
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|
C27H26F3N5O4S
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0315939
|
6-(4-tert-butylphenyl)sulfonyl-7-pyridin-3-yl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
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|
C28H25F3N4O2S
|
1
|
| 1 |
IC50 = 1.72 nM
|
|
|
|
CP0315940
|
(1R)-1-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]ethanol
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|
C27H26F3N5O4S
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0436009
|
N-methyl-1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutane-1-carboxamide
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|
C26H22F6N4O4S
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0256765
|
2-[3-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
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|
C25H19F6N5O5S
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0462865
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-6-methylpyridine
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|
C23H29N3
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0430445
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridin-2-amine
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|
C22H28N4
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0377000
|
3-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
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|
C22H27N3
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0194393
|
2-[3-[2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]sulfonyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
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|
C25H19F6N5O4S
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0402311
|
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)isothiazole
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|
C20H25N3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0365995
|
4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
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|
C24H28N2O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0390896
|
5-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)isothiazole
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|
C20H25N3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0225161
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
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|
C22H27N3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0260398
|
2-[3-[6-[4-(difluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C25H20F5N5O5S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0401480
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-5-fluoropyridine
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|
C22H26FN3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0410795
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)piperidine
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|
C22H33N3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
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CP0192143
|
3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-4H-1,2,4-oxadiazol-5-one
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|
C25H22F3N5O4S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0402312
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-pyrazole
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|
C20H26N4
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
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CP0462864
|
4'-(2-(4-(cyclohexylmethyl)-1H-imidazol-2-yl)ethyl)-4,5-difluorobiphenyl-2-carboxylic acid
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|
C25H26F2N2O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0507291
|
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1,2,3-thiadiazole
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|
C19H24N4S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0390895
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridin-2-ol
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|
C22H27N3O
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
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CP0401483
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyrazine
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|
C21H26N4
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
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CP0417715
|
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
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|
C22H27N3
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
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CP0400009
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinonitrile
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|
C23H26N4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
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CP0417714
|
2-(4-(2-(4-(cyclopentylmethyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
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|
C22H25N3
|
1
|
| 1 |
IC50 = 177 nM
|
|
|
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CP0401489
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-2H-tetrazole
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|
C18H24N6
|
1
|
| 1 |
IC50 = 205 nM
|
|
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CP0390897
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-1,2,4-triazole
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|
C19H25N5
|
1
|
| 1 |
IC50 = 340 nM
|
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CP0401488
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-1,2,3-triazole
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|
C19H25N5
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
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CP0401495
|
3-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinic acid
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|
C23H27N3O2
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
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CP0401496
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinic acid
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|
C23H27N3O2
|
1
|
| 1 |
IC50 = 2821 nM
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CP0373910
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4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)biphenyl-2-carboxylic acid
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|
C25H30N2O3
|
1
|
| 1 |
IC50 = 3676 nM
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