Brief Information of the Cell Line and Protein
Cell Line ID: CL000058 , T-REx-293
 Cell Line Info 
Synonyms
T-REx 293
T-REx293
TRex-293
TREx293
T-REx-HEK293
T-REx HEK 293
HEK293-T-REx
HEK293-Trex
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_D585
Protein ID: PT01994 , Metabotropic glutamate receptor 1
 Protein Info 
Gene Name GRM1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q13255
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000058
 Cell Line Info 
 Protein ID: PT01994
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0175902
 Compound Info 
N-[4-(1,3-dioxoisoindol-2-yl)-2-fluorophenyl]-3-methylfuran-2-carboxamide
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C20H13FN2O4
  1
1
EC50 = 12.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0683242
 Compound Info 
N-(2-fluoro-4-(5-methyl-1,3-dioxoisoindolin-2-yl)phenyl)-3-methylfuran-2-carboxamide
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C21H15FN2O4
  1
1
EC50 = 25.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0384839
 Compound Info 
N-[3-chloro-4-(4-fluoro-1,3-dioxoisoindol-2-yl)phenyl]-3-methylfuran-2-carboxamide
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C20H12ClFN2O4
  1
1
EC50 = 31.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0401813
 Compound Info 
3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide
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C20H10Cl3N3O3
  1
1
EC50 = 390 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0416254
 Compound Info 
7-(4-fluorophenyl)-2-[[2-(trifluoromethyl)pyridin-4-yl]oxymethyl]pyrazolo[1,5-a]pyrimidine-5-carboxamide
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C20H13F4N5O2
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0416287
 Compound Info 
2-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl]-7-(4-fluorophenyl)thieno[3,2-b]pyridine-5-carboxamide
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C21H22FN3O2S
  1
1
IC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS