Brief Information of the Compound and Protein
Compound Name
N-[4-(1,3-dioxoisoindol-2-yl)-2-fluorophenyl]-3-methylfuran-2-carboxamide
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PubChem ID
CID: 122196123
Canonical SMILES
Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccccc2C1=O
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Compound Formula C20H13FN2O4
Compound Structure
Protein Name
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q13255
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000058 T-REx-293 Homo sapiens (Human)  1
1
EC50 = 12.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 13 nM
2 IC50 = 12.59 nM