Brief Information of the Cell Line and Protein
Cell Line ID: CL000053 , COS-7
 Cell Line Info 
Synonyms
Cos-7
COS 7
Cos 7
COS7
Cos7
CV-1 in Origin Simian-7
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0224
Protein ID: PT01800 , Cysteinyl leukotriene receptor 1
 Protein Info 
Gene Name CYSLTR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q9Y271
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000053
 Cell Line Info 
 Protein ID: PT01800
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0231162
 Compound Info 
cyclopentyl N-[3-[[4-(benzenesulfonylcarbamoyl)-2-methoxyphenyl]methyl]-1-methylindol-5-yl]carbamate
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C30H31N3O6S
  1
1
Kd = 0.07943 nM
 Bioactivity Info 
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CP0349916
 Compound Info 
cyclopentyl N-[3-[[4-[(3-chlorophenyl)sulfonylcarbamoyl]-2-methoxyphenyl]methyl]-1-methylindol-5-yl]carbamate
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C30H30ClN3O6S
  1
1
Kd = 0.1 nM
 Bioactivity Info 
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CP0536295
 Compound Info 
4-[[5-(cyclopentylcarbamoylamino)-1-methylindol-3-yl]methyl]-3-methoxy-N-(2-methylphenyl)sulfonylbenzamide
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C31H34N4O5S
  1
1
Kd = 0.7943 nM
 Bioactivity Info 
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CP0231163
 Compound Info 
N-(3-chlorophenyl)sulfonyl-4-[[5-(cyclohexylcarbamoylamino)-1-methylindol-3-yl]methyl]-3-methoxybenzamide
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C31H33ClN4O5S
  1
1
Kd = 1.259 nM
 Bioactivity Info 
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CP0231165
 Compound Info 
N-(benzenesulfonyl)-4-[[5-(cyclohexylcarbamoylamino)-1-methylindol-3-yl]methyl]-3-methoxybenzamide
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C31H34N4O5S
  1
1
Kd = 1.995 nM
 Bioactivity Info 
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CP0248701
 Compound Info 
4-[[5-(cyclohexylcarbamoylamino)-1-methylindol-3-yl]methyl]-3-methoxy-N-[3-(trifluoromethyl)phenyl]sulfonylbenzamide
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C32H33F3N4O5S
  1
1
Kd = 5.012 nM
 Bioactivity Info 
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CP0230347
 Compound Info 
4-[[5-(cyclohexylcarbamoylamino)-1-methylindol-3-yl]methyl]-N-(3,5-dichlorophenyl)sulfonyl-3-methoxybenzamide
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C31H32Cl2N4O5S
  1
1
Kd = 6.31 nM
 Bioactivity Info 
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CP0231164
 Compound Info 
4-[[5-(cyclohexylcarbamoylamino)-1-methylindol-3-yl]methyl]-N-(3-fluorophenyl)sulfonyl-3-methoxybenzamide
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C31H33FN4O5S
  1
1
Kd = 12.59 nM
 Bioactivity Info 
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CP0116556
 Compound Info 
4-[[5-(cyclohexylcarbamoylamino)-1-methylindol-3-yl]methyl]-3-methoxy-N-(2-methylphenyl)sulfonylbenzamide
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C32H36N4O5S
  1
1
Kd = 25.12 nM
 Bioactivity Info 
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